McLean Hospital 115 Mill Street Belmont, MA 02478
McLean’s world-class researchers are published in scholarly and scientific journals on topics ranging throughout the fields of psychiatry and neuroscience.
Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior
Li S, Kumar T P, Joshee S, Kirschstein T, Subburaju S, Khalili JS, Kloepper J, Du C, Elkhal A, Szabó G, Jain RK, Köhling R, Vasudevan A. Cell Research. 2017 Oct 31. [Epub ahead of print]
Auditory attention in autism spectrum disorder: an exploration of volumetric magnetic resonance imaging findings
Lalani SJ, Duffield TC, Trontel HG, Bigler ED, Abildskov TJ, Froehlich A, Prigge MBD, Travers BG, Anderson JS, Zielinski BA, Alexander A, Lange N, Lainhart JE. Journal of Clinical and Experimental Neuropsychology. 2017 Oct 26:1-16. [Epub ahead of print]
Late-onset Alzheimer’s disease is associated with inherent changes in bioenergetics profiles
Sonntag KC, Ryu WI, Amirault KM, Healy RA, Siegel AJ, McPhie DL, Forester B, Cohen BM. Scientific Reports. 2017 Oct 25;7(1):14038.
Apathy: a neurocircuitry model based on frontotemporal dementia
Ducharme S, Price BH, Dickerson BC. Journal of Neurology, Neurosurgery, and Psychiatry. 2017 Oct 24. [Epub ahead of print]
Touchscreen technology in the study of cognition-related behavior
Kangas BD, Bergman J. Behavioural Pharmacology. 2017 Oct 23. [Epub ahead of print]
Coupling biological detection to liquid chromatography: a new tool in drug discovery
Campuzano-Bublitz MA, Hernández-Jiménez JG, González-Brito R, Montesinos MS, Fernández JJ, Díaz JG, Borges R. Naunyn-Schmiedeberg’s Archives of Pharmacology. 2017 Oct 23. [Epub ahead of print]
Nicotine increases activation to anticipatory valence cues In anterior insula and striatum
Moran LV, Stoeckel LE, Wang K, Caine CE, Villafuerte R, Calderon V, Baker JT, Ongur D, Janes AC, Pizzagalli DA, Evins AE. Nicotine & Tobacco Research. 2017 Sep 25. [Epub ahead of print]
Dopamine dysfunction in schizophrenia and bipolar disorder-never the twain shall meet?
Öngür D. JAMA Psychiatry. 2017 Oct 11. [Epub ahead of print]
Pimavanserin: novel pharmacotherapy for Parkinson’s disease psychosis
Sahli ZT, Tarazi FI. Expert Opinion on Drug Discovery. 2017 Oct 31:1-8. [Epub ahead of print]
Treatment to enhance cognition in bipolar disorder (TREC-BD): efficacy of a randomized controlled trial of cognitive remediation versus active control
Lewandowski KE, Sperry SH, Cohen BM, Norris LA, Fitzmaurice GM, Ongur D, Keshavan MS. Journal of Clinical Psychiatry. 2017 Oct 17. [Epub ahead of print]
Effects of lorcaserin (Belviq®) on nicotine- and food-maintained responding in non-human primates
Jacobs DS, Barkin CE, Kohut MR, Bergman J, Kohut SJ. Drug and Alcohol Dependence. 2017 Oct 10;181:94-101.
Changes in brain metabolic connectivity underlie autistic-like social deficits in a rat model of autism spectrum disorder
Cho H, Kim CH, Knight EQ, Oh HW, Park B, Kim DG, Park HJ. Scientific Reports. 2017 Oct 16;7(1):13213.
In vivo brain glycine and glutamate concentrations in patients with first-episode psychosis measured by echo time-averaged proton magnetic resonance spectroscopy at 4T
Kim SY, Kaufman MJ, Cohen BM, Jensen JE, Coyle JT, Du F, Öngür D. Biological Psychiatry. 2017 Sep 7. [Epub ahead of print]
The correlation between DNA methylation and transcriptional expression of human dopamine transporter in cell lines
Zhai D, Li S, Dong G, Zhou D, Yang Y, Wang X, Zhao Y, Yang Y, Lin Z. Neuroscience Letters. 2017 Oct 10;662:91-97.
Serine racemase and D-serine in the amygdala are dynamically involved in fear learning
Balu DT, Presti KT, Huang CCY, Muszynski K, Radzishevsky I, Wolosker H, Guffanti G, Ressler KJ, Coyle JT. Biological Psychiatry. 2017 Aug 26. [Epub ahead of print]
College binge drinking associated with decreased frontal activation to negative emotional distractors during inhibitory control
Cohen-Gilbert JE, Nickerson LD, Sneider JT, Oot EN, Seraikas AM, Rohan ML, Silveri MM. Frontiers in Psychology. 2017 Sep 22;8:1650.
Reduced interhemispheric executive control network coupling in men during early cocaine abstinence: a pilot study
McCarthy JM, Zuo CS, Shepherd JM, Dias N, Lukas SE, Janes AC. Drug & Alcohol Dependence. 2017 Oct 5;181:1-4.
Cannabis for the treatment of chronic pain in the era of an opioid epidemic: a symposium-based review of sociomedical science
Maher DP, Carr DB, Hill K, McGeeney B, Weed V, Jackson WC, DiBenedetto DJ, Moriarty EM, Kulich RJ. Pain Medicine. 2017 Jul 13. [Epub ahead of print]
Electrophysiological indicators of inhibitory control deficits in depression
Palmwood EN, Krompinger JW, Simons RF. Biological Psychology. 2017 Oct 3;130:1-10.
Perinatal immune activation produces persistent sleep alterations and epileptiform activity in male mice
Missig G, Mokler EL, Robbins JO, Alexander AJ, McDougle CJ, Carlezon WA. Neuropsychopharmacology. 2017 Oct 6. [Epub ahead of print]
AZI23’UTR Is a new SLC6A3 downregulator associated with an epistatic protection against substance use disorders
Liu K, Yu J, Zhao J, Zhou Y, Xiong N, Xu J, Wang T, Bell RL, Qing H, Lin Z. Molecular Neurobiology. 2017 Oct 5. [Epub ahead of print]
Emotional intelligence is associated with connectivity within and between resting state networks
Killgore WDS, Smith R, Olson EA, Weber M, Rauch SL, Nickerson LD. Social Cognitive and Affective Neuroscience. 2017 Oct 1;12(10):1624-1636.
Early onset schizophrenia associated with obsessive-compulsive disorder: clinical features and correlates
Baytunca B, Kalyoncu T, Ozel I, Erermiş S, Kayahan B, Öngur D. Clinical Neuropharmacology. 2017 Oct 2. [Epub ahead of print]
Patient-derived hiPSC neurons with heterozygous CNTNAP2 deletions display altered neuronal gene expression and network activity
Flaherty E, Deranieh RM, Artimovich E, Lee IS, Siegel AJ, Levy DL, Nestor MW, Brennand KJ. NPJ Schizophrenia. 2017 Oct 2;3:35.
Patient-derived hiPSC neurons with heterozygous CNTNAP2 deletions display altered neuronal gene expression and network activity
Flaherty E, Deranieh RM, Artimovich E, Lee IS, Siegel AJ, Levy DL, Nestor MW, Brennand KJ. NPJ Schizophrenia. 2017 Oct 2;3(1):35.
HDAC5 and its target gene, Npas4, function in the nucleus accumbens to regulate cocaine-conditioned behaviors
Taniguchi M, Carreira MB, Cooper YA, Bobadilla AC, Heinsbroek JA, Koike N, Larson EB, Balmuth EA, Hughes BW, Penrod RD, Kumar J, Smith LN, Guzman D, Takahashi JS, Kim TK, Kalivas PW, Self DW, Lin Y, Cowan CW. Neuron. 2017 Sep 27;96(1):130-144.e6.
Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury
Perez EJ, Tapanes SA, Loris ZB, Balu DT, Sick TJ, Coyle JT, Liebl DJ. Journal of Clinical Investigation. 2017 Aug 1;127(8):3114-3125.
The joint effect of prenatal exposure to metal mixtures on neurodevelopmental outcomes at 20-40 months of age: evidence from rural Bangladesh
Valeri L, Mazumdar MM, Bobb JF, Claus Henn B, Rodrigues E, Sharif OIA, Kile ML, Quamruzzaman Q, Afroz S, Golam M, Amarasiriwardena C, Bellinger DC, Christiani DC, Coull BA, Wright RO. Environmental Health Perspectives. 2017 Jun 26;125(6):067015.
Aggression protects against the onset of major depressive episodes in individuals with bipolar spectrum disorder
Ng TH, Freed RD, Titone MK, Stange JP, Weiss RB, Abramson LY, Alloy LB. Behavior Therapy. 2017 May;48(3):311-321.
Misclassified exposure in epigenetic mediation analyses. Does DNA methylation mediate effects of smoking on birthweight?
Valeri L, Reese SL, Zhao S, Page CM, Nystad W, Coull BA, London SJ. Epigenomics. 2017 Mar;9(3):253-265.
Unbiased metabolite profiling of schizophrenia fibroblasts under stressful perturbations reveals dysregulation of plasmalogens and phosphatidylcholines
Huang JH, Park H, Iaconelli J, Berkovitch SS, Watmuff B, McPhie D, Öngür D, Cohen BM, Clish CB, Karmacharya R. Journal of Proteome Research. 2017 Feb 3;16(2):481-493.
Oral cannabidiol does not produce a signal for abuse liability in frequent marijuana smokers
Babalonis S, Haney M, Malcolm RJ, Lofwall MR, Votaw VR, Sparenborg S, Walsh SL. Drug and Alcohol Dependence. 2017 Mar 1;172:9-13.
Age at menarche predicts age at onset of major affective and anxiety disorders
Tondo L, Pinna M, Serra G, De Chiara L, Baldessarini RJ. European Psychiatry. 2017 Jan;39:80-85.
Perisylvian GABA levels in schizophrenia and bipolar disorder
Atagün Mİ, Sıkoglu EM, Soykan Ç, Serdar Süleyman C, Ulusoy-Kaymak S, Çayköylü A, Algın O, Phillips ML, Öngür D, Moore CM. Neuroscience Letters. 2017 Jan 10;637:70-74.
Stress and reward processing in bipolar disorder: a functional magnetic resonance imaging study
Berghorst LH, Kumar P, Greve DN, Deckersbach T, Ongur D, Dutra SJ, Pizzagalli DA. Bipolar Disorders. 2016 Nov;18(7):602-611.
Description and prediction of the income status of borderline patients over 10 years of prospective follow-up
Niesten IJ, Karan E, Frankenburg FR, Fitzmaurice GM, Zanarini MC. Personality and Mental Health. 2016 Nov;10(4):285-292.
Delay discounting in opioid use disorder: differences between heroin and prescription opioid users
Karakula SL, Weiss RD, Griffin ML, Borges AM, Bailey AJ, McHugh RK. Drug and Alcohol Dependence. 2016 Dec 1;169:68-72.
Trait-related alterations of N-acetylaspartate in euthymic bipolar patients: a longitudinal proton magnetic resonance spectroscopy study
Aydin B, Yurt A, Gökmen N, Renshaw P, Olson D, Yildiz A. Journal of Affective Disorders. 2016 Dec;206:315-320.
Special issue on the adolescent brain
Spear LP, Silveri MM. Neuroscience and Biobehavioral Reviews. 2016 Nov;70:1-3.
Commentary on the special issue on the adolescent brain: adolescence, trajectories, and the importance of prevention
Andersen SL. Neuroscience and Biobehavioral Reviews. 2016 Nov;70:329-333.
Neurobiological signatures associated with alcohol and drug use in the human adolescent brain
Silveri MM, Dager AD, Cohen-Gilbert JE, Sneider JT. Neuroscience and Biobehavioral Reviews. 2016 Nov;70:244-259.
Qualitative analysis of a psychological supportive counseling group for burn survivors and families in Malawi
Barnett BS, Mulenga M, Kiser MM, Charles AG. Burns. 2017 May;43(3):602-607.
Psychophysical study of face identity discrimination in schizophrenia: association with facial morphology
Ekstrom T, Maher S, Chen Y. Cognitive Neuropsychiatry. 2016 Nov;21(6):525-538.
Using iPSC-derived human DA neurons from opioid-dependent subjects to study dopamine dynamics
Sheng Y, Filichia E, Shick E, Preston KL, Phillips KA, Cooperman L, Lin Z, Tesar P, Hoffer B, Luo Y. Brain and Behavior. 2016 May 25;6(8):e00491.
Dorsal anterior cingulate glutamate is associated with engagement of the default mode network during exposure to smoking cues
Janes AC, Betts J, Jensen JE, Lukas SE. Drug and Alcohol Dependence. 2016 Oct 1;167:75-81.
Gene expression-based screen for Parkinson’s disease identifies GW8510 as a neuroprotective agent
Wimalasena NK, Le VQ, Wimalasena K, Schreiber SL, Karmacharya R. ACS Chemical Neuroscience. 2016 Jul 20;7(7):857-63.
Common use of electroconvulsive therapy for Chinese adolescent psychiatric patients
Zhang QE, Wang ZM, Sha S, Ng CH, Seiner SJ, Welch CA, Lok GK, Chow IH, Wang F, Li L, Xiang YT. Journal of ECT. 2016 Dec;32(4):251-255.
Forebrain glutamatergic, but not GABAergic, neurons mediate anxiogenic effects of the glucocorticoid receptor
Hartmann J, Dedic N, Pöhlmann ML, Häusl A, Karst H, Engelhardt C, Westerholz S, Wagner KV, Labermaier C, Hoeijmakers L, Kertokarijo M, Chen A, Joëls M, Deussing JM, Schmidt MV. Molecular Psychiatry. 2017 Mar;22(3):466-475.
Responding to the call for improving resident wellness
Chaukos D, Vestal HS, Bernstein C. Academic Medicine. 2016 Jun;91(6):750.
Longitudinal association between pain severity and subsequent opioid use in prescription opioid dependent patients with chronic pain
Griffin ML, McDermott KA, McHugh RK, Fitzmaurice GM, Jamison RN, Weiss RD. Drug and Alcohol Dependence. 2016 Jun 1;163:216-21.
A ‘complex’ of brain metabolites distinguish altered chemistry in the cingulate cortex of episodic migraine patients
Becerra L, Veggeberg R, Prescot A, Jensen JE, Renshaw P, Scrivani S, Spierings EL, Burstein R, Borsook D. NeuroImage Clinical. 2016 Mar 31;11:588-94.
Assessing anhedonia in depression: potentials and pitfalls
Rizvi SJ, Pizzagalli DA, Sproule BA, Kennedy SH. Neuroscience and Biobehavioral Reviews. 2016 Jun;65:21-35.
Lifetime and 12-month nonsuicidal self-injury and academic performance in college freshmen
Kiekens G, Claes L, Demyttenaere K, Auerbach RP, Green JG, Kessler RC, Mortier P, Nock MK, Bruffaerts R. Suicide & Life-Threatening Behavior. 2016 Oct;46(5):563-576.
Prevalence and course of sexual relationship difficulties in recovered and non-recovered patients with borderline personality disorder over 16 years of prospective follow-up
Karan E, Niesten IJ, Frankenburg FR, Fitzmaurice GM, Zanarini MC. Personality and Mental Health. 2016 Aug;10(3):232-43.
Transplantation of human retinal pigment epithelial cells in the nucleus accumbens of cocaine self-administering rats provides protection from seeking
Venkiteswaran K, Alexander DN, Puhl MD, Rao A, Piquet AL, Nyland JE, Subramanian MP, Iyer P, Boisvert MM, Handly E, Subramanian T, Grigson PS. Brain Research Bulletin. 2016 May;123:53-60.
Variability and anatomical specificity of the orbitofrontothalamic fibers of passage in the ventral capsule/ventral striatum (VC/VS): precision care for patient-specific tractography-guided targeting of deep brain stimulation (DBS) in obsessive compulsive disorder (OCD)
Makris N, Rathi Y, Mouradian P, Bonmassar G, Papadimitriou G, Ing WI, Yeterian EH, Kubicki M, Eskandar EN, Wald LL, Fan Q, Nummenmaa A, Widge AS, Dougherty DD. Brain Imaging and Behavior. 2016 Dec;10(4):1054-1067.
Mapping anhedonia-specific dysfunction in a transdiagnostic approach: an ALE meta-analysis
Zhang B, Lin P, Shi H, Öngür D, Auerbach RP, Wang X, Yao S, Wang X. Brain Imaging and Behavior. 2016 Sep;10(3):920-39.