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McLean Institute for Technology in Psychiatry

Below are some examples of current projects taking place at or in collaboration with the McLean Institute for Technology in Psychiatry (ITP). In each project, the goal is to improve our ability to understand or improve mental health and create systems that meet patients where they are through personalized, digital solutions that can be made widely available.

Smartphone-Based Treatment Interventions

In partnership with Valera Health, ITP is working with McLean OnTrackTM to develop a mobile application to enable earlier detection of changes in mental health status among patients with severe mental illnesses. This application includes a clinician dashboard and tools for digital case management that integrate with existing behavioral health systems. Currently, the application is part of an investigator-initiated clinical trial to understand how well it performs in a naturalistic clinical setting.

Lead investigators: Justin T. Baker, MD, PhD, Dost Öngür, MD, PhD

Cognitive Assessment in the Wild

TestMyBrain is a web-based cognitive assessment platform that takes advantage of the strong public interest in the mind and brain as an engine for scientific advancement. Since 2008, over 1.6 million people have participated in a study on TestMyBrain.org. Using this data, we are improving the resolution and accuracy of traditional cognitive assessments for research and clinical care. We are also creating new methods for understanding how people differ from one another in their cognitive functions and how these differences might be related to mental health.

Lead investigator: Laura Germine, PhD

Digital Phenotyping in Mental Illness

Beiwe is the world’s first fully encrypted smartphone platform for continuous monitoring of patients with severe mental illness coupled to world class machine classifiers. The goal of Beiwe is to build a clinical warning system capable of detecting and adapting to complex changes in behavior, while they are happening or even before. This will enable clinicians to help identify and support patients during the times when they need it most.

Lead investigators: JP Onnela, Justin T. Baker, MD, PhD

The Last Mile Problem in Psychiatry

The MultiSense project uses video to capture naturalistic face-to-face clinical interviews. We then use these videos in combination with machine learning to improve the efficiency and robustness of mental health assessments through automatic sensing. The goal of the MultiSense project is to improve patient care and enable high-throughput behavioral characterizations for conventional clinical trials.

Lead investigators: Justin T. Baker, MD, PhD, Liz Liebson, Joseph Stoklosa, MD, Louis-Philippe Morency