McLean Hospital 115 Mill Street Belmont, MA 02478
McLean’s world-class researchers are published in scholarly and scientific journals on topics ranging throughout the fields of psychiatry and neuroscience.
Rostral anterior cingulate cortex morphology predicts treatment response to internet-based cognitive behavioral therapy for depression
Webb CA, Olson EA, Killgore WDS, Pizzagalli DA, Rauch SL, Rosso IM. Biological Psychiatry Cognitive Neuroscience and Neuroimaging. 2018 Mar;3(3):255-262.
Depression is associated with dimensional and categorical effects on white matter pathways
Dillon DG, Gonenc A, Belleau E, Pizzagalli DA. Depression and Anxiety. 2018 Feb 27. [Epub ahead of print]
Fiction reading has a small positive impact on social cognition: a meta-analysis
Dodell-Feder D, Tamir DI. Journal of Experimental Psychology General. 2018 Feb 26. [Epub ahead of print]
Concurrent assessment of the antinociceptive and behaviorally disruptive effects of opioids in squirrel monkeys
Withey SL, Paronis CA, Bergman J. Journal of Pain. 2018 Feb 22. [Epub ahead of print]
Anhedonic behavior and γ-amino butyric acid during a sensitive period in female rats exposed to early adversity
Lukkes JL, Meda S, Norman KJ, Andersen SL. Journal of Psychiatric Research. 2018 Feb 13;100:8-15.
Mast cells regulate CD4+ T cell differentiation in absence of antigen presentation
Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Camacho V, Minami K, Nian Y, Koduru S, El Fatimy R, Ghiran I, Trachtenberg AJ, de la Fuente MA, Azuma H, Akbari O, Tullius SG, Vasudevan A, Elkhal A. Journal of Allergy and Clinical Immunology. 2018 Feb 19. [Epub ahead of print]
Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine
Fischer KD, Houston ACW, Desai RI, Doyle MR, Bergman J, Mian M, Mannix R, Sulzer DL, Choi SJ, Mosharov EV, Hodgson NW, Bechtholt A, Miczek KA, Rosenberg PA. Psychopharmacology (Berl). 2018 Feb 22. [Epub ahead of print]
So Tired: predictive utility of baseline sleep screening in a longitudinal observational survey cohort of first-year residents
Zebrowski JP, Pulliam SJ, Denninger JW, Berkowitz LR. Journal of General Internal Medicine. 2018 Feb 20. [Epub ahead of print]
N-acetylcysteine in a double-blind randomized placebo-controlled trial: toward biomarker-guided treatment in early psychosis
Conus P, Seidman LJ, Fournier M, Xin L, Cleusix M, Baumann PS, Ferrari C, Cousins A, Alameda L, Gholam-Rezaee M, Golay P, Jenni R, Woo TW, Keshavan MS, Eap CB, Wojcik J, Cuenod M, Buclin T, Gruetter R, Do KQ. Schizophrenia Bulletin. 2018 Feb 15;44(2):317-327.
Demographic and clinical characteristics associated with a history of bizarre delusions in a cross-diagnostic sample of individuals with psychotic disorders
Yuksel C, Yilmaz S, Nesbit A, Carkaxhiu G, Ravichandran C, Salvatore P, Pingali S, Cohen B, Ongur D. Asian Journal of Psychiatry. 2018 Feb 9;31:82-85.
Evaluating effects of prenatal exposure to phthalate mixtures on birth weight: a comparison of three statistical approaches
Chiu YH, Bellavia A, James-Todd T, Correia KF, Valeri L, Messerlian C, Ford JB, Mínguez-Alarcón L, Calafat AM, Hauser R, Williams PL; EARTH Study Team. Environment International. 2018 Feb 13;113:231-239.
Different perception levels of histamine-induced itch sensation in young adult mice
Ji Y, Jang Y, Lee WJ, Yang YD, Shim WS. Physiology and Behavior. 2018 Feb 9;188:188-193.
Depressive residual symptoms are associated with illness course characteristics in a sample of outpatients with bipolar disorder
Serafini G, Vazquez GH, Gonda X, Pompili M, Rihmer Z, Amore M. European Archives of Psychiatry and Clinical Neuroscience. 2018 Feb 7. [Epub ahead of print]
Alpha-adrenergic receptors in PTSD – failure or time for precision medicine?
Ressler KJ. New England Journal of Medicine. 2018 Feb 8;378(6):575-576.
The role of serine racemase in the pathophysiology of brain disorders
Coyle JT, Balu DT. Advances in Pharmacology. 2018;82:35-56.
Innovation and integrity in intervention research: conceptual issues, methodology, and knowledge translation
Malti T, Beelmann A, Noam GG, Sommer S. Prevention Science. 2018 Feb 6. [Epub ahead of print]
Intranuclear delivery of the transcription modulation domain of Tbet-improved lupus nephritis in (NZB/NZW) F1 lupus-prone mice
Moon JS, Mun CH, Kim JH, Cho JY, Park SD, Park TY, Shin JS, Ho CC, Park YB, Ghosh S, Bothwell ALM, Lee SW, Lee SK. Kidney International. 2018 Feb 3. [Epub ahead of print]
Description and prediction of time-to-attainment of excellent recovery for borderline patients followed prospectively for 20 years
Zanarini MC, Temes CM, Frankenburg FR, Reich DB, Fitzmaurice GM. Psychiatry Research. 2018 Feb 1;262:40-45.
Weight loss and malnutrition in patients with Parkinson’s disease: current knowledge and future prospects
Ma K, Xiong N, Shen Y, Han C, Liu L, Zhang G, Wang L, Guo S, Guo X, Xia Y, Wan F, Huang J, Lin Z, Wang T. Frontiers in Aging Neuroscience. 2018 Jan 19;10:1.
Early onset tobacco cigarette smokers exhibit deficits in response inhibition and sustained attention
Mashhoon Y, Betts J, Farmer SL, Lukas SE. Drug and Alcohol Dependence. 2018 Mar 1;184:48-56.
Hippocampal subfields volume reduction in high schoolers with previous verbal abuse experiences
Lee SW, Yoo JH, Kim KW, Kim D, Park H, Choi J, Teicher MH, Jeong B. Clinical Psychopharmacology and Neuroscience. 2018 Feb 28;16(1):46-56.
Electroencephalography source functional connectivity reveals abnormal high-frequency communication among large-scale functional networks in depression
Whitton AE, Deccy S, Ironside ML, Kumar P, Beltzer M, Pizzagalli DA. Biological Psychiatry Cognitive Neuroscience and Neuroimaging. 2018 Jan;3(1):50-58.
Optical imaging of ovarian cancer using a matrix metalloproteinase-3-sensitive near-infrared fluorescent probe
Wang KH, Wang YM, Chiu LH, Chen TC, Tsai YH, Zuo CS, Chen KC, Changou CA, Lai WT. PLoS One. 2018 Feb 1;13(2):e0192047.
Mechanisms of change in treatments of personality disorders: commentary on the special section
Gunderson JG. Journal of Personality Disorders. 2018 Jan;32(Supplement):129-133.
The grass might be greener: medical marijuana patients exhibit altered brain activity and improved executive function after 3 months of treatment
Gruber SA, Sagar KA, Dahlgren MK, Gonenc A, Smith RT, Lambros AM, Cabrera KB, Lukas SE. Frontiers in Pharmacology. 2018 Jan 17;8:983.
Anatomical axes of the proximal and distal halves of the femur in a normally aligned healthy population: implications for surgery
Yazdi H, Nazarian A, Kwon JY, Hochman MG, Pakdaman R, Hafezi P, Ghahremani M, Joudi S, Ghorbanhoseini M. Journal of Orthopaedic Surgery and Research. 2018 Jan 31;13(1):21.
Hastening treatment development in bipolar disorder: evaluation of consensus-based recommendations for cognition trials
Lewandowski KE. Bipolar Disorders. 2018 Feb;20(1):70-71.
What are physicians’ responsibilities to patients whose health conditions can influence their legal proceedings?
Beckmann D. AMA Journal of Ethics. 2017 Sep 1;19(9):877-884.
Lurasidone: efficacy and safety in the treatment of psychotic and mood disorders
Pompili M, Verzura C, Trovini G, Buscajoni A, Falcone G, Naim S, Nardella A, Sorice S, Baldessarini RJ, Girardi P. Expert Opinion on Drug Safety. 2018 Feb;17(2):197-205.
Single-stage cartilage repair using platelet-rich fibrin scaffolds with autologous cartilaginous grafts
Wong CC, Chen CH, Chan WP, Chiu LH, Ho WP, Hsieh FJ, Chen YT, Yang TL. American Journal of Sports Medicine. 2017 Nov;45(13):3128-3142.
Investigating causal relation between prenatal arsenic exposure and birthweight: are smaller infants more susceptible?
Rahman ML, Valeri L, Kile ML, Mazumdar M, Mostofa G, Qamruzzaman Q, Rahman M, Baccarelli A, Liang L, Hauser R, Christiani DC. Environment International. 2017 Nov;108:32-40.
Lysine deacetylation by HDAC6 regulates the kinase activity of AKT in human neural progenitor cells
Iaconelli J, Lalonde J, Watmuff B, Liu B, Mazitschek R, Haggarty SJ, Karmacharya R. ACS Chemical Biology. 2017 Aug 18;12(8):2139-2148.
Dicer and microRNAs protect adult dopamine neurons
Chmielarz P, Konovalova J, Najam SS, Alter H, Piepponen TP, Erfle H, Sonntag KC, Schütz G, Vinnikov IA, Domanskyi A. Cell Death & Disease. 2017 May 25;8(5):e2813.
Treatment of bipolar disorder in a lifetime perspective: is lithium still the best choice?
Sani G, Perugi G, Tondo L. Clinical Drug Investigation. 2017 Aug;37(8):713-727.
Technology-based interventions for substance use and comorbid disorders: an examination of the emerging literature
Sugarman DE, Campbell ANC, Iles BR, Greenfield SF. Harvard Review of Psychiatry. 2017 May/Jun;25(3):123-134.
Internet-based cognitive-behavioral therapy for depression: current progress and future directions
Webb CA, Rosso IM, Rauch SL. Harvard Review of Psychiatry. 2017 May/Jun;25(3):114-122.
Regional 18F-fluorodeoxyglucose hypometabolism is associated with higher apathy scores over time in early Alzheimer disease
Gatchel JR, Donovan NJ, Locascio JJ, Becker JA, Rentz DM, Sperling RA, Johnson KA, Marshall GA; Alzheimer’s Disease Neuroimaging Initiative. American Journal of Geriatric Psychiatry. 2017 Jul;25(7):683-693.
International suicide rates versus adequate treatments
Baldessarini RJ, Tondo L. British Journal of Psychiatry. 2017 Apr;210(4):298-299.
Early clinical predictors and correlates of long-term morbidity in bipolar disorder
Serra G, Koukopoulos A, De Chiara L, Koukopoulos AE, Sani G, Tondo L, Girardi P, Reginaldi D, Baldessarini RJ. European Psychiatry. 2017 Jun;43:35-43.
Disruption of white matter structural integrity and connectivity in posttraumatic stress disorder: a TBSS and tractography study
Olson EA, Cui J, Fukunaga R, Nickerson LD, Rauch SL, Rosso IM. Depression and Anxiety. 2017 May;34(5):437-445.
Methodology and reporting of mobile heath and smartphone application studies for schizophrenia
Torous J, Firth J, Mueller N, Onnela JP, Baker JT. Harvard Review of Psychiatry. 2017 May/Jun;25(3):146-154.
Mobile assessment of heightened skin conductance in posttraumatic stress disorder
Hinrichs R, Michopoulos V, Winters S, Rothbaum AO, Rothbaum BO, Ressler KJ, Jovanovic T. Depression and Anxiety. 2017 Jun;34(6):502-507.
The association of psychedelic use and opioid use disorders among illicit users in the United States
Pisano VD, Putnam NP, Kramer HM, Franciotti KJ, Halpern JH, Holden SC. Journal of Psychopharmacology. 2017 May;31(5):606-613.
Electroconvulsive therapy (ECT) for treating agitation in dementia (major neurocognitive disorder) - a promising option
Glass OM, Forester BP, Hermida AP. International Psychogeriatrics. 2017 May;29(5):717-726.
Comparison of a non-stationary voxelation-corrected cluster-size test with TFCE for group-level MRI inference
Li H, Nickerson LD, Nichols TE, Gao JH. Human Brain Mapping. 2017 Mar;38(3):1269-1280.
Microstructural brain abnormalities in medication-free patients with major depressive disorder: a systematic review and meta-analysis of diffusion tensor imaging
Jiang J, Zhao YJ, Hu XY, Du MY, Chen ZQ, Wu M, Li KM, Zhu HY, Kumar P, Gong QY. Journal of Psychiatry and Neuroscience. 2017 May;42(3):150-163.
Brain levels of high-energy phosphate metabolites and executive function in geriatric depression
Harper DG, Joe EB, Jensen JE, Ravichandran C, Forester BP. International Journal of Geriatric Psychiatry. 2016 Nov;31(11):1241-1249.
Endogenous co-agonists of the NMDA receptor modulate contextual fear in trace conditioning
Basu AC, Puhl MD, Coyle JT. Neurobiology of Learning and Memory. 2016 Dec;136:244-250.
Finland in Boston? Applying open dialogue ideals on a psychotic disorders inpatient teaching unit
Rosen K, Stoklosa J. Psychiatric Services. 2016 Dec 1;67(12):1283-1285.
Effects of accountable care and payment reform on substance use disorder treatment: evidence from the initial 3 years of the alternative quality contract
Stuart EA, Barry CL, Donohue JM, Greenfield SF, Duckworth K, Song Z, Mechanic R, Kouri EM, Ebnesajjad C, Chernew ME, Huskamp HA. Addiction. 2017 Jan;112(1):124-133.
Late-life depression: a role for accelerometer technology in diagnosis and management
Vahia IV, Sewell DD. American Journal of Psychiatry. 2016 Aug 1;173(8):763-8.
Bridging the gap: towards a cell-type specific understanding of neural circuits underlying fear behaviors
McCullough KM, Morrison FG, Ressler KJ. Neurobiology of Learning and Memory. 2016 Nov;135:27-39.
Estimating causal contrasts involving intermediate variables in the presence of selection bias
Valeri L, Coull BA. Statistics in Medicine. 2016 Nov 20;35(26):4779-4793.
The 6-month effectiveness of internet-based guided self-help for depression in adults with type 1 and 2 diabetes mellitus
Ebert DD, Nobis S, Lehr D, Baumeister H, Riper H, Auerbach RP, Snoek F, Cuijpers P, Berking M. Diabetic Medicine. 2017 Jan;34(1):99-107.
EphB3 signaling propagates synaptic dysfunction in the traumatic injured brain
Perez EJ, Cepero ML, Perez SU, Coyle JT, Sick TJ, Liebl DJ. Neurobiology of Disease. 2016 Oct;94:73-84.
(11)C[double bond, length as m-dash]O bonds made easily for positron emission tomography radiopharmaceuticals
Rotstein BH, Liang SH, Placzek MS, Hooker JM, Gee AD, Dollé F, Wilson AA, Vasdev N. Chemical Society Reviews. 2016 Aug 22;45(17):4708-26.
New insights in the systemic and molecular underpinnings of general anesthetic actions mediated by γ-aminobutyric acid A receptors
Antkowiak B, Rudolph U. Current Opinion in Anaesthesiology. 2016 Aug;29(4):447-53.
Stem cell models of neuropsychiatric disorders
Karmacharya R, Haggarty SJ. Molecular and Cellular Neurosciences. 2016 Jun;73:1-2.
SSRI enhances sensitivity to background outcomes and modulates response rates: a randomized double blind study of instrumental action and depression
Msetfi RM, Kumar P, Harmer CJ, Murphy RA. Neurobiology of Learning and Memory. 2016 May;131:76-82.
Harnessing smartphone-based digital phenotyping to enhance behavioral and mental health
Onnela JP, Rauch SL. Neuropsychopharmacology. 2016 Jun;41(7):1691-6.
Disease signatures for schizophrenia and bipolar disorder using patient-derived induced pluripotent stem cells
Watmuff B, Berkovitch SS, Huang JH, Iaconelli J, Toffel S, Karmacharya R. Molecular and Cellular Neurosciences. 2016 Jun;73:96-103.
In vivo modeling of neuronal function, axonal impairment and connectivity in neurodegenerative and neuropsychiatric disorders using induced pluripotent stem cells
Korecka JA, Levy S, Isacson O. Molecular and Cellular Neurosciences. 2016 Jun;73:3-12.
Environmental enrichment facilitates cocaine-cue extinction, deters reacquisition of cocaine self-administration and alters AMPAR GluA1 expression and phosphorylation
Gauthier JM, Lin A, Nic Dhonnchadha BÁ, Spealman RD, Man HY, Kantak KM. Addiction Biology. 2017 Jan;22(1):152-162.