McLean Hospital 115 Mill Street Belmont, MA 02478
McLean’s world-class researchers are published in scholarly and scientific journals on topics ranging throughout the fields of psychiatry and neuroscience.
Fear extinction recall modulates human frontomedial theta and amygdala activity
Sperl MFJ, Panitz C, Rosso IM, Dillon DG, Kumar P, Hermann A, Whitton AE, Hermann C, Pizzagalli DA, Mueller EM. Cerebral Cortex. 2018 Jan 24. [Epub ahead of print]
Public health impact of androgens
Kanayama G, Kaufman MJ, Pope HG Jr. Current Opinion in Endocrinology, Diabetes, and Obesity. 2018 Jan 24. [Epub ahead of print]
Patient- and technician-oriented attitudes toward transcranial magnetic stimulation devices
Lonergan B, Nguyen E, Lembo C, Hinchman C, Morales OG, Press DZ, Pascual-Leone A, Stern AP. Journal of Neuropsychiatry and Clinical Neuroscience. 2018 Jan 25: [Epub ahead of print]
Time-dependent differences in cortical measures and their associations with behavioral measures following mild traumatic brain injury
Bajaj S, Dailey NS, Rosso IM, Rauch SL, Killgore WDS. Hum Brain Mapping. 2018 Jan 22. [Epub ahead of print]
Income inequality and depression: a systematic review and meta-analysis of the association and a scoping review of mechanisms
Patel V, Burns JK, Dhingra M, Tarver L, Kohrt BA, Lund C. World Psychiatry. 2018 Feb;17(1):76-89.
Cell type-specific laser capture microdissection for gene expression profiling in the human brain
Mauney SA, Woo TW, Sonntag KC. Methods in Molecular Biology. 2018;1723:203-221.
Suicidal thoughts and behaviors among college students and same-aged peers: results from the World Health Organization World Mental Health Surveys
Mortier P, Auerbach RP, Alonso J, Axinn WG, Cuijpers P, Ebert DD, Green JG, Hwang I, Kessler RC, Liu H, Nock MK, Pinder-Amaker S, Sampson NA, Zaslavsky AM, Abdulmalik J, Aguilar-Gaxiola S, Al-Hamzawi A, Benjet C, Demyttenaere K, Florescu S, De Girolamo G, Gureje O, Haro JM, Hu C, Huang Y, De Jonge P, Karam EG, Kiejna A, Kovess-Masfety V, Lee S, Mcgrath JJ, O’neill S, Nakov V, Pennell BE, Piazza M, Posada-Villa J, Rapsey C, Viana MC, Xavier M, Bruffaerts R. Social Psychiatry and Psychiatric Epidemiology. 2018 Jan 16. [Epub ahead of print]
The resting-state fMRI arterial signal predicts differential blood transit time through the brain
Tong Y, Yao JF, Chen JJ, Frederick BD. Journal of Cerebral Blood Flow Metabolism. 2018 Jan 1:271678X17753329. [Epub ahead of print]
Mechanisms of sex differences in fear and posttraumatic stress disorder
Ramikie TS, Ressler KJ. Biological Psychiatry. 2017 Nov 21. [Epub ahead of print]
Mechanisms of memory disruption in depression
Dillon DG, Pizzagalli DA. Trends in Neuroscience. 2018 Jan 10. [Epub ahead of print]
Learning situated emotions
Lebois LAM, Wilson-Mendenhall CD, Simmons WK, Barrett LF, Barsalou LW. Neuropsychologia. 2018 Jan 9. [Epub ahead of print]
Association of suicidal risk with ratings of affective temperaments
Tondo L, Vázquez GH, Sani G, Pinna M, Baldessarini RJ. Journal of Affective Disorders. 2018 Jan 3;229:322-327.
Nociceptive roles of TRPM2 ion channel in pathologic pain
Jang Y, Cho PS, Yang YD, Hwang SW. Molecular Neurobiology. 2018 Jan 11. [Epub ahead of print]
Levy DL, Bragg TA. Neuropsychopharmacology. 2018 Feb;43(3):673.
Longitudinal association of amyloid beta and anxious-depressive symptoms in cognitively normal older adults
Donovan NJ, Locascio JJ, Marshall GA, Gatchel J, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA; Harvard Aging Brain Study. American Journal of Psychiatry. 2018 Jan 12 [Epub ahead of print]
Current directions in laboratory studies of personality pathology: examples from borderline personality disorder, psychopathy, and schizotypy
Matusiewicz AK, McCauley KL, McCarthy JM, Bounoua N, Lejuez CW. Personality Disorders. 2018 Jan;9(1):2-11
Decreased taurine and creatine in the thalamus may relate to behavioral impairments in ethanol-fed mice: a pilot study of proton magnetic resonance spectroscopy
Xu S, Zhu W, Wan Y, Wang J, Chen X, Pi L, Lobo MK, Ren B, Ying Z, Morris M, Cao Q. Molecular Imaging. 2018 Jan-Dec;17:1536012117749051.
Rare Loss of function mutations in N-Methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility
Yu Y, Lin Y, Takasaki Y, Wang C, Kimura H, Xing J, Ishizuka K, Toyama M, Kushima I, Mori D, Arioka Y, Uno Y, Shiino T, Nakamura Y, Okada T, Morikawa M, Ikeda M, Iwata N, Okahisa Y, Takaki M, Sakamoto S, Someya T, Egawa J, Usami M, Kodaira M, Yoshimi A, Oya-Ito T, Aleksic B, Ohno K, Ozaki N. Translational Psychiatry. 2018 Jan 10;8(1):12.
Long-lasting in vivo effects of the cannabinoid CB1 antagonist AM6538
Paronis CA, Chopda GR, Vemuri K, Zakarian AS, Makriyannis A, Bergman J. Journal of Pharmacology and Experimental Therapy. 2018 Jan 8. [Epub ahead of print]
An ERP study of multidimensional source retrieval in depression
Barrick EM, Dillon DG. Biological Psychology. 2018 Jan 3;132:176-191.
Astrocytes in primary cultures express serine racemase, synthesize D-serine and acquire A1 reactive astrocyte features
Li S, Uno Y, Rudolph U, Cobb J, Liu J, Anderson T, Levy D, Balu DT, Coyle JT. Biochemical Pharmacology. 2018 Jan 3. [Epub ahead of print]
Suicidal risk and affective temperaments, evaluated with the TEMPS-A scale: a systematic review
Vázquez GH, Gonda X, Lolich M, Tondo L, Baldessarini RJ. Harvard Review of Psychiatry. 2018 Jan/Feb;26(1):8-18.
Clinical and environmental risk factors for bipolar disorder: review of prospective studies
Marangoni C, Faedda GL, Baldessarini RJ. Harvard Review of Psychiatry. 2018 Jan/Feb;26(1):1-7.
Distress tolerance as a mediator of the association between borderline personality symptoms and obsessive relational intrusion: an exploratory analysis
Reilly ME, Hines DA. Journal of Interpersonal Violence. 2017 Jun 1:886260517712274. [Epub ahead of print]
Childhood maltreatment, limbic dysfunction, resilience, and psychiatric symptoms
Ashy M, Yu B, Gutowski E, Samkavitz A, Malley-Morrison K. Journal of Interpersonal Violence. 2017 Jan 1:886260516683174. [Epub ahead of print]
Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements
Pirhaji L, Milani P, Dalin S, Wassie BT, Dunn DE, Fenster RJ, Avila-Pacheco J, Greengard P, Clish CB, Heiman M, Lo DC, Fraenkel E. Nature Communications. 2017 Sep 20;8(1):623.
Behavioral methods to study anxiety in rodents
Lezak KR, Missig G, Carlezon WA Jr. Dialogues in Clinical Neuroscience. 2017 Jun;19(2):181-191.
Cortical pyramidal neurons show a selective loss of new synapses in chronic schizophrenia
Coyle JT. American Journal of Psychiatry. 2017 Jun 1;174(6):510-511.
Muscarinic receptor M4 positive allosteric modulators attenuate central effects of cocaine
Dall C, Weikop P, Dencker D, Molander AC, Wörtwein G, Conn PJ, Fink-Jensen A, Thomsen M. Drug and Alcohol Dependence. 2017 Jul 1;176:154-161.
Mild, moderate, meaningful? Examining the psychological and functioning correlates of DSM-5 eating disorder severity specifiers
Gianini L, Roberto CA, Attia E, Walsh BT, Thomas JJ, Eddy KT, Grilo CM, Weigel T, Sysko R. International Journal of Eating Disorders. 2017 Aug;50(8):906-916.
Time course of the effects of lisdexamfetamine dimesylate in two phase 3, randomized, double-blind, placebo-controlled trials in adults with binge-eating disorder
McElroy SL, Hudson JI, Gasior M, Herman BK, Radewonuk J, Wilfley D, Busner J. International Journal of Eating Disorders. 2017 Aug;50(8):884-892.
Bipolar mood state reflected in cortico-amygdala resting state connectivity: a cohort and longitudinal study
Brady RO Jr, Margolis A, Masters GA, Keshavan M, Öngür D. Journal of Affective Disorders. 2017 Aug 1;217:205-209.
Frequency of non-right-handedness in bipolar disorder and schizophrenia
Ravichandran C, Shinn AK, Öngür D, Perlis RH, Cohen B. Psychiatry Research. 2017 Jul;253:267-269.
The 10-year course of adult aggression toward others in patients with borderline personality disorder and axis II comparison subjects
Zanarini MC, Temes CM, Ivey AM, Cohn DM, Conkey LC, Frankenburg FR, Fitzmaurice GM. Psychiatry Research. 2017 Jun;252:134-138.
Biomarkers, designs, and interpretations of resting-state fMRI in translational pharmacological research: a review of state-of-the-art, challenges, and opportunities for studying brain chemistry
Khalili-Mahani N, Rombouts SA, van Osch MJ, Duff EP, Carbonell F, Nickerson LD, Becerra L, Dahan A, Evans AC, Soucy JP, Wise R, Zijdenbos AP, van Gerven JM. Hum Brain Mapping. 2017 Apr;38(4):2276-2325.
Factors associated with antidepressant dosing in Asia: findings from the research on Asian psychotropic prescription study
Rajaratnam K, Xiang YT, Tripathi A, Chiu HF, Si TM, Chee KY, Avasthi A, Grover S, Chong MY, Kuga H, Kanba S, He YL, Lee MS, Yang SY, Udomratn P, Kallivayalil RA, Tanra AJ, Maramis M, Shen WW, Sartorius N, Kua EH, Tan CH, Mahendran R, Shinfuku N, Sum MY, Baldessarini RJ, Sim K. Journal of Clinical Psychopharmacology. 2016 Dec;36(6):716-719.
Clozapine modulates glucosylceramide, clears aggregated proteins, and enhances ATG8/LC3 in Caenorhabditis elegans
Hao L, Ben-David O, Babb SM, Futerman AH, Cohen BM, Buttner EA. Neuropsychopharmacology. 2017 Mar;42(4):951-962.
A review of abnormalities in the perception of visual illusions in schizophrenia
King DJ, Hodgekins J, Chouinard PA, Chouinard VA, Sperandio I. Psychonomic Bulletin and Review. 2017 Jun;24(3):734-751.
Clinical observations about the potential benefits and pitfalls of between-session contacts with borderline patients
Jacob KL. Harvard Review of Psychiatry. 2016 Sep-Oct;24(5):e8-e14.
“Good enough” psychiatric residency training in borderline personality disorder: challenges, choice points, and a model generalist curriculum
Unruh BT, Gunderson JG. Harvard Review of Psychiatry. 2016 Sep-Oct;24(5):367-77.
Evidence-based treatments for borderline personality disorder: implementation, integration, and stepped care
Choi-Kain LW, Albert EB, Gunderson JG. Harvard Review of Psychiatry. 2016 Sep-Oct;24(5):342-56.
Tissue type-specific bioenergetic abnormalities in adults with major depression
Harper DG, Jensen JE, Ravichandran C, Perlis RH, Fava M, Renshaw PF, Iosifescu DV. Neuropsychopharmacology. 2017 Mar;42(4):876-885.
Anxiety sensitivity and nonmedical benzodiazepine use among adults with opioid use disorder
McHugh RK, Votaw VR, Bogunovic O, Karakula SL, Griffin ML, Weiss RD. Addictive Behaviors. 2017 Feb;65:283-288.
Perceived risk of heroin use among nonmedical prescription opioid users
Votaw VR, Wittenauer J, Connery HS, Weiss RD, McHugh RK. Addictive Behaviors. 2017 Feb;65:218-223.
Inflammation in fear- and anxiety-based disorders: PTSD, GAD, and beyond
Michopoulos V, Powers A, Gillespie CF, Ressler KJ, Jovanovic T. Neuropsychopharmacology. 2017 Jan;42(1):254-270.
Preventative treatment in an animal model of ADHD: behavioral and biochemical effects of methylphenidate and its interactions with ovarian hormones in female rats
Lukkes JL, Freund N, Thompson BS, Meda S, Andersen SL. European Neuropsychopharmacology. 2016 Sep;26(9):1496-1506. Erratum in: European Neuropsychopharmacology. 2016 Nov;26(11):1843.
LRRK2 Interferes with aggresome formation for autophagic clearance
Bang Y, Kim KS, Seol W, Choi HJ. Molecular and Cellular Neuroscience. 2016 Sep;75:71-80.
Depression with mixed features in adolescent psychiatric patients
Frazier EA, Swenson LP, Mullare T, Dickstein DP, Hunt JI. Child Psychiatry and Human Development. 2017 Jun;48(3):393-399.
Brain activity and connectivity in response to negative affective stimuli: impact of dysphoric mood and sex across diagnoses
Mareckova K, Holsen LM, Admon R, Makris N, Seidman L, Buka S, Whitfield-Gabrieli S, Goldstein JM. Hum Brain Mapping. 2016 Nov;37(11):3733-3744.
Cognitive vulnerability to major depression: view from the intrinsic network and cross-network interactions
Wang X, Öngür D, Auerbach RP, Yao S. Harvard Review of Psychiatry. 2016 May-Jun;24(3):188-201.
Oral r-(-)-11-O-valeryl-N-n-propylnoraporphine reverses motor deficits in MPTP-treated marmosets
Lincoln L, Fisher R, Jackson MJ, Jenner P, Neumeyer J, Sromek AW, Lees AJ, Rose S. Movement Disorders. 2016 Sep;31(9):1381-8.
The emergence of a generalist model to meet public health needs for patients with borderline personality disorder
Gunderson JG. American Journal of Psychiatry. 2016 May 1;173(5):452-8.
Impact of persistent and adolescent-limited antisocial behaviour on adult health outcomes
Paradis AD, Koenen KC, Fitzmaurice GM, Buka SL. Journal of Epidemiology and Community Health. 2016 Oct;70(10):1004-10.
Ultra-high performance liquid chromatography with tandem mass spectrometry method for the simultaneous quantitation of five phthalides in rat plasma: application to a comparative pharmacokinetic study of Huo Luo Xiao Ling Dan and herb-pair extract
Ma W, Wang W, Peng Y, Bian Q, Wang N, Lee DY, Dai R. Journal of Separation Science. 2016 Jun;39(11):2057-67.
Blockade of nicotine and cannabinoid reinforcement and relapse by a cannabinoid CB1-receptor neutral antagonist AM4113 and inverse agonist rimonabant in squirrel monkeys
Schindler CW, Redhi GH, Vemuri K, Makriyannis A, Le Foll B, Bergman J, Goldberg SR, Justinova Z. Neuropsychopharmacology. 2016 Aug;41(9):2283-93.
Association between a brief alcohol craving measure and drinking in the following week
McHugh RK, Fitzmaurice GM, Griffin ML, Anton RF, Weiss RD. Addiction. 2016 Jun;111(6):1004-10.
An mGlu5-positive allosteric modulator rescues the neuroplasticity deficits in a genetic model of NMDA receptor hypofunction in schizophrenia
Balu DT, Li Y, Takagi S, Presti KT, Ramikie TS, Rook JM, Jones CK, Lindsley CW, Conn PJ, Bolshakov VY, Coyle JT. Neuropsychopharmacology. 2016 Jul;41(8):2052-61.
Psychological treatment of depression in college students: a meta-analysis
Cuijpers P, Cristea IA, Ebert DD, Koot HM, Auerbach RP, Bruffaerts R, Kessler RC. Depression and Anxiety. 2016 May;33(5):400-14.
Dynamic resting-state functional connectivity in major depression
Kaiser RH, Whitfield-Gabrieli S, Dillon DG, Goer F, Beltzer M, Minkel J, Smoski M, Dichter G, Pizzagalli DA. Neuropsychopharmacology. 2016 Jun;41(7):1822-30.
Fibroblast biomarkers of sporadic Parkinson’s disease and LRRK2 kinase inhibition
Smith GA, Jansson J, Rocha EM, Osborn T, Hallett PJ, Isacson O. Molecular Neurobiology. 2016 Oct;53(8):5161-77.
Differentiation of human pluripotent stem cells into medial ganglionic eminence vs. caudal ganglionic eminence cells
Ahn S, Kim TG, Kim KS, Chung S. Methods. 2016 May 15;101:103-12.