McLean Hospital 115 Mill Street Belmont, MA 02478
McLean’s world-class researchers are published in scholarly and scientific journals on topics ranging throughout the fields of psychiatry and neuroscience.
Effects of acute and chronic treatments with dopamine D2 and D3 receptor ligands on cocaine versus food choice in rats
Thomsen M, Barrett AC, Butler P, Negus SS, Caine SB. Journal of Pharmacology and Experimental Therapeutics. 2017 Jul;362(1):161-176.
Modeling schizophrenia pathogenesis using patient-derived induced pluripotent stem cells (iPSCs)
Noh H, Shao Z, Coyle JT, Chung S. Biochimica et Biophysica Acta. 2017 Jun 28. [Epub ahead of print]
Memory retention involves the ventrolateral orbitofrontal cortex: comparison with the basolateral amygdala
Zimmermann KS, Li C, Rainnie DG, Ressler KJ, Gourley SL. Neuropsychopharmacology. 2017 Jun 30. [Epub ahead of print]
Split-brain phenomena in anterior communicating artery aneurysm rupture: a case report
Korsakova N, Liebson E, Moskovich L. Psych Journal. 2017 Jun;6(2):120-136.
Aspects of tryptophan and nicotinamide adenine dinucleotide in immunity: a new twist in an old tale
Rodriguez Cetina Biefer H, Vasudevan A, Elkhal A. International Journal of Tryptophan Research. 2017 Jun 14;10:1178646917713491. eCollection 2017.
Chronic sleep restriction increases negative implicit attitudes toward Arab Muslims
Alkozei A, Killgore WDS, Smith R, Dailey NS, Bajaj S, Haack M. Scientific Reports. 2017 Jun 27;7(1):4285.
An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders
Kuan PF, Waszczuk MA, Kotov R, Marsit CJ, Guffanti G, Gonzalez A, Yang X, Koenen K, Bromet E, Luft BJ. Translational Psychiatry. 2017 Jun 27;7(6):e1158.
A transdiagnostic examination of decreased intolerance of uncertainty and treatment outcome
Stevens K, Rogers T, Campbell M, Björgvinsson T, Kertz S. Cognitive Behaviour Therapy. 2017 Jun 26:1-15. [Epub ahead of print]
Integrated molecular landscape of Parkinson’s disease
Klemann CJHM, Martens GJM, Sharma M, Martens MB, Isacson O, Gasser T, Visser JE, Poelmans G. NPJ Parkinson’s Disease. 2017 Apr 10;3:14. eCollection 2017.
Perineuronal nets in the adult sensory cortex are necessary for fear learning
Banerjee SB, Gutzeit VA, Baman J, Aoued HS, Doshi NK, Liu RC, Ressler KJ. Neuron. 2017 Jun 15. [Epub ahead of print]
Data security and privacy in apps for dementia: an analysis of existing privacy policies
Rosenfeld L, Torous J, Vahia IV. American Journal of Geriatric Psychiatry. 2017 Jun 1. [Epub ahead of print]
Cognitive deficits in prematurely born adults are associated with reduced basal forebrain integrity
Balu DT. Biological Psychiatry. 2017 Jul 15;82(2):e15-e16.
Age invariance in rapid facial affective reactions to emotionally valenced stimuli
Nangle MR, Bailey PE, Henry JD, Khlentzos GS, Varcin KJ, Whitton AE. Quarterly Journal of Experimental Psychology (Hove). 2017 Jun 23:1-37. [Epub ahead of print]
A risk algorithm for the persistence of suicidal thoughts and behaviors during college
Mortier P, Kiekens G, Auerbach RP, Cuijpers P, Demyttenaere K, Green JG, Kessler RC, Nock MK, Zaslavsky AM, Bruffaerts R. Journal of Clinical Psychiatry. 2017 Jun 20. [Epub ahead of print]
Novel role and regulation of HDAC4 in cocaine-related behaviors
Penrod RD, Carreira MB, Taniguchi M, Kumar J, Maddox SA, Cowan CW. Addiction Biology. 2017 Jun 21. [Epub ahead of print]
Exact Bayesian p-values for a test of independence in a 2 x 2 contingency table with missing data
Lin Y, Lipsitz SR, Sinha D, Fitzmaurice G, Lipshultz S. Statistical Methods in Medical Research. 2017 Jan 1:962280217702538 [Epub ahead of print]
Direct comparison of tricyclic and serotonin-reuptake inhibitor antidepressants in randomized head-to-head trials in acute major depression: Systematic review and meta-analysis
Undurraga J, Baldessarini RJ. Journal of Psychopharmacology. 2017 Jun 1:269881117711709. [Epub ahead of print]
Increased neural response to social rejection in major depression
Kumar P, Waiter GD, Dubois M, Milders M, Reid I, Steele JD. Depression and Anxiety. 2017 Jun 20. [Epub ahead of print]
Development of novel behavioral interventions in an experimental therapeutics world: challenges, and directions for the future
Lewandowski KE, Ongur D, Keshavan MS. Schizophrenia Research. 2017 Jun 16. [Epub ahead of print]
Electrocortical reactivity during self-referential processing in female youth with borderline personality disorder
Auerbach RP, Tarlow N, Bondy E, Stewart JG, Aguirre B, Kaplan C, Yang W, Pizzagalli DA. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. 2016 Jul;1(4):335-344.
Restless legs syndrome: from pathophysiology to clinical diagnosis and management
Guo S, Huang J, Jiang H, Han C, Li J, Xu X, Zhang G, Lin Z, Xiong N, Wang T. Frontier in Aging Neuroscience. 2017 Jun 2;9:171.
The implication of neuronimmunoendocrine (NIE) modulatory network in the pathophysiologic process of Parkinson’s disease
Shen Y, Guo X, Han C, Wan F, Ma K, Guo S, Wang L, Xia Y, Liu L, Lin Z, Huang J, Xiong N, Wang T. Cellular and Molecular Life Sciences. 2017 Jun 16. [Epub ahead of print]
Increases of calbindin-containing chandelier cartridges in schizophrenia: fact or artifact?
Benes FM. Biological Psychiatry. 2017 Jul 1;82(1):4-5.
Presenilins regulate synaptic plasticity and mitochondrial calcium homeostasis in the hippocampal mossy fiber pathway
Lee SH, Lutz D, Mossalam M, Bolshakov VY, Frotscher M, Shen J. Molecular Neurodegeneration. 2017 Jun 15;12(1):48.
Interactive voice response calls to promote smoking cessation after hospital discharge: pooled analysis of two randomized clinical trials
Rigotti NA, Chang Y, Rosenfeld LC, Japuntich SJ, Park ER, Tindle HA, Levy DE, Reid ZZ, Streck J, Gomperts T, Kelley JHK, Singer DE. Journal of General Internal Medicine. 2017 Jun 14. [Epub ahead of print]
Differential depression of neuronal network activity by midazolam and its main metabolite 1-hydroxymidazolam in cultured neocortical slices
Balk M, Hentschke H, Rudolph U, Antkowiak B, Drexler B. Scientific Reports. 2017 Jun 14;7(1):3503.
Personality disorder, borderline
Chapman J, Fleisher C. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2017 Jun-.
Cognitive mechanisms and therapeutic targets of addiction
Copersino ML. Current Opinion in Behavioral Science. 2017 Feb;13:91-98.
Running out of time: clock copying as a psychometric to predict mortality in vulnerable older adults?
Gatchel JR, Forester BP. American Journal of Geriatric Psychiatry. 2017 May 15. [Epub ahead of print]
Psychosocial functioning in adolescents with and without borderline personality disorder
Kramer U, Temes CM, Magni LR, Fitzmaurice GM, Aguirre BA, Goodman M, Zanarini MC. Personality and Mental Health. 2017 Jun 8. [Epub ahead of print]
Developmental effects of antipsychotic drugs on serotonin receptor subtypes
Choi YK, Gardner MP, Tarazi FI. Synapse. 2017 Jun 8. [Epub ahead of print]
Dexamethasone facilitates fear extinction and safety discrimination in PTSD: A placebo-controlled, double-blind study
Michopoulos V, Norrholm SD, Stevens JS, Glover EM, Rothbaum BO, Gillespie CF, Schwartz AC, Ressler KJ, Jovanovic T. Psychoneuroendocrinology. 2017 May 31;83:65-71.
Health effects of dramatic societal events - ramifications of the recent presidential election
Williams DR, Medlock MM. New England Journal of Medicine. 2017 Jun 8;376(23):2295-2299.
Prodepressant- and anxiogenic-like effects of serotonin-selective, but not noradrenaline-selective, antidepressant agents in mice lacking α2-containing GABAA receptors
Benham RS, Hewage NB, Suckow RF, Engin E, Rudolph U. Behavioural Brain Research. 2017 Jun 3;332:172-179.
Isolated mitochondria transfer improves neuronal differentiation of schizophrenia-derived induced pluripotent stem cells and rescues deficits in a rat model of the disorder
Robicsek O, Ene HM, Karry R, Ytzhaki O, Asor E, McPhie D, Cohen BM, Ben-Yehuda R, Weiner I, Ben-Shachar D. Schizophrenia Bulletin. 2017 Jun 6. [Epub ahead of print]
Reply: Capgras syndrome: neuroanatomical assessment of brain MRI findings in an adolescent patient
Darby RR, Fox MD. Brain. 2017 Jul 1;140(7):e44.
Defining the impact of childhood adversities on cognitive deficits in psychosis: An exploratory analysis
Schalinski I, Teicher MH, Carolus AM, Rockstroh B. Schizophrenia Research. 2017 May 30. [Epub ahead of print]
Cortical pyramidal neurons show a selective loss of new synapses in chronic schizophrenia
Coyle JT. American Journal of Psychiatry. 2017 Jun 1;174(6):510-511.
Skin conductance responses and neural activations during fear conditioning and extinction recall across anxiety disorders
Marin MF, Zsido RG, Song H, Lasko NB, Killgore WDS, Rauch SL, Simon NM, Milad MR. JAMA Psychiatry. 2017 Jun 1;74(6):622-631.
The communicative function of sad facial expressions
Reed LI, DeScioli P. Evolutionary Psychology. 2017 Jan-Mar;15(1):1474704917700418.
Functional connectivity of the subcallosal cingulate cortex and differential outcomes to treatment with cognitive-behavioral therapy or antidepressant medication for major depressive disorder
Dunlop BW, Rajendra JK, Craighead WE, Kelley ME, McGrath CL, Choi KS, Kinkead B, Nemeroff CB, Mayberg HS. American Journal of Psychiatry. 2017 Jun 1;174(6):533-545.
Treatment of major depressive disorder with Iyengar yoga and coherent breathing: a randomized controlled dosing study
Streeter CC, Gerbarg PL, Whitfield TH, Owen L, Johnston J, Silveri MM, Gensler M, Faulkner CL, Mann C, Wixted M, Hernon AM, Nyer MB, Brown ER, Jensen JE. Journal of Alternative and Complementary Medicine. 2017 Mar;23(3):201-207.
Clinical use of mood stabilizers with antidepressants in Asia: report from the research on Asian psychotropic prescription patterns for antidepressants (REAP-AD) projects in 2004 and 2013
Rajaratnam K, Xiang YT, Tripathi A, Chiu HF, Si TM, Chee KY, Avasthi A, Grover S, Chong MY, Kuga H, Kanba S, He YL, Lee MS, Yang SY, Udomratn P, Kallivayalil RA, Tanra AJ, Maramis MM, Shen WW, Sartorius N, Kua EH, Tan CH, Mahendran R, Shinfuku N, Sum MY, Baldessarini RJ, Sim K. Journal of Clinical Psychopharmacology. 2017 Apr;37(2):255-259.
Demonstrating test-retest reliability of electrophysiological measures for healthy adults in a multisite study of biomarkers of antidepressant treatment response
Tenke CE, Kayser J, Pechtel P, Webb CA, Dillon DG, Goer F, Murray L, Deldin P, Kurian BT, McGrath PJ, Parsey R, Trivedi M, Fava M, Weissman MM, McInnis M, Abraham K, E Alvarenga J, Alschuler DM, Cooper C, Pizzagalli DA, Bruder GE. Psychophysiology. 2017 Jan;54(1):34-50.
Simultaneous determination of l-tetrahydropalmatine and its active metabolites in rat plasma by a sensitive ultra-high-performance liquid chromatography with tandem mass spectrometry method and its application in a pharmacokinetic study
Wang W, Liu J, Zhao X, Peng Y, Wang N, Lee DYW, Dai R. Biomedical Chromatography. 2017 Jun;31(6).
Administration of electroconvulsive therapy for depression associated with deep brain stimulation in a patient with post-traumatic Parkinson’s disease: a case study
Cunningham MG, Yadollahikhales G, Vitaliano G, van Horne C. BMC Psychiatry. 2016 Nov 15;16(1):399.
Effects of Gabra2 point mutations on alcohol intake: increased binge-like and blunted chronic drinking by mice
Newman EL, Gunner G, Huynh P, Gachette D, Moss SJ, Smart TG, Rudolph U, DeBold JF, Miczek KA. Alcoholism, Clinical and Experimental Research. 2016 Nov;40(11):2445-2455.
Vertebral volumetric bone density and strength are impaired in women with low-weight and atypical anorexia nervosa
Bachmann KN, Schorr M, Bruno AG, Bredella MA, Lawson EA, Gill CM, Singhal V, Meenaghan E, Gerweck AV, Slattery M, Eddy KT, Ebrahimi S, Koman SL, Greenblatt JM, Keane RJ, Weigel T, Misra M, Bouxsein ML, Klibanski A, Miller KK. Journal of Clinical Endocrinology and Metabolism. 2017 Jan 1;102(1):57-68.
Clinical management of restless legs syndrome in end-stage renal disease patients
Sahli ZT, Jo J, Mousa SA, Tarazi FI. CNS Spectrums. 2017 Feb;22(1):14-21.
Genome-wide association study of positive emotion identifies a genetic variant and a role for microRNAs
Wingo AP, Almli LM, Stevens JS, Jovanovic T, Wingo TS, Tharp G, Li Y, Lori A, Briscione M, Jin P, Binder EB, Bradley B, Gibson G, Ressler KJ. Molecular Psychiatry. 2017 May;22(5):774-783.
Preclinical PET neuroimaging of [11C]Bexarotene
Rotstein BH, Placzek MS, Krishnan HS, Pekošak A, Collier TL, Wang C, Liang SH, Burstein ES, Hooker JM, Vasdev N. Molecular Imaging. 2016 Aug 23;15.
Predictors of rehospitalization for depressed adolescents admitted to acute psychiatric treatment
van Alphen NR, Stewart JG, Esposito EC, Pridgen B, Gold J, Auerbach RP. Journal of Clinical Psychiatry. 2017 May;78(5):592-598.
Prioritizing individual genetic variants after kernel machine testing using variable selection
He Q, Cai T, Liu Y, Zhao N, Harmon QE, Almli LM, Binder EB, Engel SM, Ressler KJ, Conneely KN, Lin X, Wu MC. Genetic Epidemiology. 2016 Dec;40(8):722-731.
The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia
Ralvenius WT, Acuña MA, Benke D, Matthey A, Daali Y, Rudolph U, Desmeules J, Zeilhofer HU, Besson M. Neuropharmacology. 2016 Oct;109:366-75.
Novel C-ring-hydroxy-substituted controlled deactivation cannabinergic analogues
Kulkarni S, Nikas SP, Sharma R, Jiang S, Paronis CA, Leonard MZ, Zhang B, Honrao C, Mallipeddi S, Raghav JG, Benchama O, Järbe TU, Bergman J, Makriyannis A. Journal of Medicinal Chemistry. 2016 Jul 28;59(14):6903-19.
The McLean-Harvard first-episode project: early course in 114 cases of first-episode nonaffective psychoses
Tohen M, Khalsa HM, Salvatore P, Zarate CA Jr, Strakowski SM, Sanchez-Toledo JP, Baldessarini RJ. Journal of Clinical Psychiatry. 2016 Jun;77(6):781-8.
Eating disorder symptoms in middle-aged and older men
Mangweth-Matzek B, Kummer KK, Pope HG. International Journal of Eating Disorders. 2016 Oct;49(10):953-957.
Limited predictability of postmortem human brain tissue quality by RNA integrity numbers
Sonntag KC, Tejada G, Subburaju S, Berretta S, Benes FM, Woo TU. Journal of Neurochemistry. 2016 Jul;138(1):53-9.
Improved low-cost, MR-compatible olfactometer to deliver tobacco smoke odor
Lowen SB, Farmer SL, Lukas SE. Behavior Research Methods. 2017 Feb;49(1):74-82.
Diagnosing, disclosing, and documenting borderline personality disorder: a survey of psychiatrists’ practices
Sisti D, Segal AG, Siegel AM, Johnson R, Gunderson J. Journal of Personality Disorders. 2016 Dec;30(6):848-856.