Mclean Hospital
Natalia Luchkina, PhD

Natalia V. Luchkina, PhD

McLean Hospital Title:
Harvard Medical School Title:
  • Research Fellow in Psychiatry


Natalia V. Luchkina, PhD, received her PhD degree from the University of Helsinki in Finland. During her graduate studies, Dr. Luchkina explored a developmental profile of mechanisms underlying the induction and expression of long-term-potentiation at CA3-CA1 synapses in the hippocampus. Her results linked the expression of GluA4 subunits of the AMPA receptor to alterations in signaling requirements for the induction of long-term potentiation, explaining the switch in LTP kinase dependency during synapse maturation. She found that GluA4 subunit expression may define the signaling requirements for LTP and silent synapse activation during a critical period of synapse development and also demonstrated that maturation of glutamatergic synapses involves a critical period during which presynaptic function is highly susceptible to activity-dependent regulation through a PKC-dependent mechanism.

In the Bolshakov laboratory at McLean, Dr. Luchkina uses optogenetics to explore how brain functions underlying complex behavioral processes are regulated.


Basic NeurosciencePharmacology


PubMed search for Dr. Luchkina

Education & Training:

  • 2007 BS in Biology/Biophysics, Saint Petersburg State University, Saint Petersburg, Russia
  • 2009 MS in Neuroscience, Saint Petersburg University, Saint Petersburg, Russia
  • 2016 PhD in Physiology and Neuroscience, University of Helsinki, Helsinki, Finland
  • 2010 CIMO Fellowship, Centre for International Mobility
  • 2011-2013 Doctoral Research Fellowship, Finnish Graduate School of Neuroscience
  • 2016-Present Post-Doctoral Research Fellow, McLean Hospital, Harvard Medical School
  • 2017-2018 Phyllis and Jerome Lyle Rappaport Mental Health Research Fellowship, McLean Hospital
  • 2019-2020 Eric Dorris Memorial Research Fellowship, McLean Hospital




Office Address:

Belmont campus - Mailman Research Center, Room 208

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