Mclean Hospital

Autism Related Content


Pathways Academy: Meeting the Needs of Students With Autism

“Every child deserves and must have the opportunity to learn and reach their full potential…” Started in 2000, McLean Hospital’s Pathways Academy is a year-round school designed and dedicated to meeting the psychological, social, and academic needs of students aged 6 to 22 with autism spectrum disorder (ASD). There are two educators for every four students at Pathways,...

Neuroscientists Reveal How Brain Circuits Are Affected by Infections in Mothers and Newborns

McLean Hospital neuroscientists have found that immune system activation during pregnancy and right at birth can cause alterations in an offspring's brain neural circuits during young adulthood that are consistent with behavioral symptoms common in autism spectrum disorder (ASD) and other developmental conditions. The detailed findings are available in the March 28, 2018, issue of the Journal of...

Teamsters Local 25 Autism Fund Presents More Than $300,000 to 11 Local Autism Non-Profits

Teamsters Local 25 president Sean O’Brien recently presented more than $300,000 to local non-profits, including a $50,000 donation to McLean Hospital which will be used to continue groundbreaking autism research and support the McLean-Franciscan Child and Adolescent Inpatient Program at Franciscan Children’s Hospital, the only Massachusetts inpatient child psychiatric program with a...

Helping Students Succeed

For some children and adolescents with autism spectrum disorders, going to school can be a difficult, anxiety-provoking proposition. Those with disorders along the autism spectrum often have issues with anxiety, learning social skills and responding to sensory stimulation. They may struggle with understanding social cues and making friends. Change of routine may be disruptive and arouse anxiety...

Autism-Related Protein Shown to Play Vital Role in Addiction

In a paper published in the latest issue of the neuroscience journal Neuron, McLean Hospital investigators report that a gene essential for normal brain development, and previously linked to autism spectrum disorders, also plays a critical role in addiction-related behaviors. “In our lab, we investigate the brain mechanisms behind drug addiction—a common and devastating disease with...

Autism Risk Gene Controls Normal Brain Wiring, Report McLean Hospital Researchers

In a paper published by the Proceedings of the National Academy of Sciences, McLean Hospital researchers and collaborators report that a gene family linked to autism, EphB, is essential for proper brain wiring during development. These findings suggest that abnormal brain wiring that results from mutations in this gene family could contribute to autism symptoms. “Using animal models, we...

Exploring the Biological Basis of Autism

One way to begin to understand the causes and effects of psychiatric illnesses is to examine the brain on the cellular level. More specifically, scientists look at how cells function on an individual level and how they interact with other cells in the brain. The Integrative Neurobiology Laboratory at McLean is dedicated exclusively to this approach. Led by Chris Cowan, PhD, the lab is...

McLean Hospital Researcher Says Intensive, Early Therapy Helps Children with Autism Improve Communication Skills

In an article appearing in the October issue of Scientific American, McLean Hospital biostatistician Nicholas Lange, ScD, asserts that although the road to more accurate diagnosis and treatment of a disease as complex as autism is long, some existing therapies are already showing lasting effects, and more are on the horizon. “Autism is a complex disease with multiple causes, differing...

Training Trade: OCD Clinicians Learn about Autism

At the OCD Institute, we are constantly working to stay abreast of the most up-to-date treatments for our patients so that we can provide the highest-quality care. This includes reading new research, attending conferences and workshops, and talking with our colleagues across the country about what techniques they are finding most useful in their practice. We are always assessing, both objectively...

Great Expectations: One Student’s Road to Success at Pathways Academy

Jeffery Lindeland is a two-sport athlete for Belmont High School who successfully fundraises on behalf of his teams and is reaching academic goals in a grade-level math class. Five years ago, his mother, Joy Anne Moses, did not know any of these things were possible. Diagnosed with a cognitive and expressive speech delay during an early intervention evaluation when he was two, Lindeland’s...

McLean Hospital Researcher to Receive New NIH Funding as Part of Autism Centers of Excellence

Nicholas Lange, ScD, director of the Neurostatistics Laboratory at McLean Hospital and associate professor of psychiatry at Harvard Medical School, is collaborating with one of the two latest research networks to be been awarded $5.3 million in initial one-year funding from the National Institutes of Health as part of the Autism Centers of Excellence (ACE) Treatment Network program. Lange is...

Although Valuable, Brain Imaging Alone Cannot Diagnose Autism

In a column appearing in the current issue of the journal Nature, McLean Hospital biostatistician Nicholas Lange, ScD, cautions against heralding the use of brain imaging scans to diagnose autism and urges greater focus on conducting large, long-term multicenter studies to identify the biological basis of the disorder. “Several studies in the past two years have claimed that brain scans...

University of Utah and Harvard Researchers Take Major Step Toward First Biological Test for Autism

Researchers at Harvard-affiliated McLean Hospital and the University of Utah have developed the best biologically-based test for autism to date. The test was able to detect the disorder in individuals with high-functioning autism with 94 percent accuracy. The study will be published in the online edition of Autism Research on Thursday, Dec. 2 (PubMed PMID 21182212). The test, which uses MRI to...

Bill Carlezon, PhD

Bill Carlezon, PhD, has received several awards for his research, including an Independent Investigator Award from the National Alliance for Research on Schizophrenia and Depression (NARSAD), the Presidential Early Career Award for Scientists and Engineers (PECASE) from George W. Bush, and the Jacob P. Waletzky Award for Innovative Research in Drug Addiction and Alcoholism from the Society for...

Tatjana Dujmic, MD, PhD

Tatjana Dujmic, MD, PhD, grew up in Croatia, a small Mediterranean country in the heart of Europe. She received her medical training from the University of Zagreb Medical School and graduated summa cum laude in 1992. Dr. Dujmic immigrated to the United States in 2000 to follow her dream and pursue a clinical career. Initially, she worked as a researcher at the Department of Psychiatry at Stanford...

Nicholas T. Lange, ScD

During his career, Dr. Lange has led and supported multidisciplinary teams of biostatisticians and other scientists in basic, translational, and clinical research on the developing brain in health and illness. Since taking a major career risk in 1996 to leave academic biostatistics and join the team at McLean Hospital, he is now a recognized leader in neurostatistics at local, national, and...

David Yue-Wei Lee, PhD

Dr. Lee has worked on numerous drug discovery projects related to traditional Chinese medicine, contributing significantly to the development of alternative therapies for substance abuse and for osteoarthritis. He is the principal investigator on “Alternative Therapies for Alcohol and Drug Abuse,” a program project grant funded by the National Institutes of Health. Under this program...

Deborah L. Levy, PhD

Deborah L. Levy, PhD, has a national and international reputation in the area of psychotic disorders, especially schizophrenia and bipolar disorder. The primary focus of her research is identifying risk genes and understanding their biological actions. Dr. Levy has been a clinical and research psychologist on the staff at McLean since 1991, and has served on the editorial board of various...

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