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Algorithm Identifies Patients Best Suited for Antidepressants

McLean Hospital researchers have completed a study that sought to determine which individuals with depression are best suited for antidepressant medications. Their findings, published in Psychological Medicine on July 2, 2018, have led to the development of a statistical algorithm that identifies patients who may best respond to antidepressants—before they begin treatment. Christian A. Webb, PhD...

McLean Scientists: Brain Activity Can Predict Success of Depression Treatment

McLean Hospital and Harvard Medical School researchers believe they have uncovered a method that could be useful in predicting a depressed patient’s treatment prognosis, prior to starting treatment. In the paper “Pretreatment Rostral Anterior Cingulate Cortex Activity in Relation to Symptom Improvement in Depression: A Randomized Clinical Trial,” available online and in the June 2018 edition of...

Two of McLean’s Researchers Receive Prestigious Pope Award

McLean researchers Christian A. Webb, PhD, assistant neuroscientist in the Laboratory for Translational and Affective Neuroscience, and W. Brad Ruzicka, MD, PhD, assistant neuroscientist in the Mailman Research Center, are winners of the 25th annual Alfred Pope Award for Young Investigators, McLean’s highest research honor. They each presented their research at a special Grand Rounds lecture on...