Mclean Hospital

Depression Related Content


Algorithm Identifies Patients Best Suited for Antidepressants

McLean Hospital researchers have completed a study that sought to determine which individuals with depression are best suited for antidepressant medications. Their findings, published in Psychological Medicine on July 2, 2018, have led to the development of a statistical algorithm that identifies patients who may best respond to antidepressants—before they begin treatment. Results of this...

Foundations Support Study on the Benefit of Yoga for Adolescent Depression

Yoga has become ubiquitous. In fact, it is difficult to find a community that doesn’t offer classes ranging from “flow” and “hot” yoga to those with nearly unpronounceable names. Tracing roots back more than 5,000 years, yoga is an array of techniques or practices aimed at integrating mind, body, and spirit to promote mindfulness, personal exploration, and a...

Study on Social Interactions Could Improve Understanding of Mental Health Risks

McLean Hospital investigators have released the results of a study that outlines how age, socioeconomic status, and other factors might contribute to social isolation and poorer mental health. In a paper published in the online version of Clinical Psychological Science, the researchers examine how individuals of all ages and walks of life seek and enjoy social interactions. Because studies have...

Running Against Stigma, Not Away From It

On April 17, 2017, Ana Febres-Cordero, a suicide survivor, and her father Rafael ran the Boston Marathon to support public awareness and outreach programs focused on eliminating the stigma surrounding mental illness. Ana was inspired to partner with McLean Hospital to develop Deconstructing Stigma: Ana’s Marathon Fund because of a shared mission to eliminate the obstacles that discourage...

Brudnick Family Funds Adolescent Depression Research

Irving Brudnick’s struggle with chronic depression began in his late teens and, according to his widow, Betty, the disease troubled him for much of his adult life. A successful businessman, educator, and philanthropist, Brudnick was passionate about putting his time and charitable resources toward causes that meant a great deal to him, including violence prevention, conflict resolution,...

McLean Scientists: Brain Activity Can Predict Success of Depression Treatment

McLean Hospital and Harvard Medical School researchers believe they have uncovered a method that could be useful in predicting a depressed patient’s treatment prognosis, prior to starting treatment. In the paper “Pretreatment Rostral Anterior Cingulate Cortex Activity in Relation to Symptom Improvement in Depression: A Randomized Clinical Trial,” available online and in the...

McLean Clinicians Assist with Theatrical Production About Depression and Suicide

Through the month of March, Boston’s SpeakEasy Stage Company is presenting “Every Brilliant Thing,” a one-character play that looks at the issues surrounding suicide. Each Thursday during the run of the show, the company is hosting post-performance discussion sessions in which audience members can talk about their experiences with depression and suicide. Clinicians from McLean...

ECT Shouldn’t Be a Last-Resort Treatment

Brian Neville had a good life. A one-time body builder, he was 43, a successful businessman in the tanning industry, with a home in Massachusetts and a vacation condo in Florida. Then one morning in 2006 he woke up with the blues. It developed into a persistent darkness that just would not go away. After about six months, he sought treatment. He received prescription medications that he was...

Understanding the Biology Behind Major Depressive Disorder

Major depressive disorder (MDD) affects about seven percent of people in the United States each year. Although researchers and clinicians know that stressful life events can trigger a depressive episode, the biological mechanisms behind it are not well understood. Studies led by Diego A. Pizzagalli, PhD, director of the Center for Depression, Anxiety and Stress Research (CDASR) at McLean Hospital...

Kayla’s Road to Victory: Taking Care of Her Mental Health

The road to success is often neither short nor smooth. Kayla Harrison of Danvers, Massachusetts, is a two-time Olympic gold medalist and the first American to win gold in judo. But she has not always been joyful and confident, as she was when she delivered the commencement address at McLean Hospital’s Arlington School 2017 graduation ceremony. Kayla’s pursuit of judo gold, she told...

Running Against Stigma: Suicide Survivor Running Boston Marathon to Raise Mental Health Awareness

On April 17, 2017, Ana Febres-Cordero, a suicide survivor, and her father Rafael will run the Boston Marathon to support public awareness and outreach programs focused on eliminating the stigma surrounding mental illness. Ana was inspired to partner with McLean Hospital to develop Deconstructing Stigma: Ana’s Marathon Fund because of a shared mission to eliminate the obstacles that...

Depression and Suicide in Adolescents: A McLean Researcher Searches for New Answers

In his lab at McLean Hospital, Randy P. Auerbach, PhD, ABPP, is using wide-ranging technological advances to improve our understanding of why certain depressed youth develop depression and engage in suicidal behaviors. “Identifying markers [objectively observable signs of disease] that improve early diagnosis of depression in youth will have profound consequences across a patient’s...

Depression Screening: Help Yourself, Help Others

National Depression Screening Day, held on October 6 this year, helps raise awareness about depression and the importance of getting screened. McLean Hospital is proud to partner again with Mental Health, Inc., to promote mental health screening and help connect people with appropriate resources for getting help. McLean Hospital is proud to promote National Depression Screening DayVisit...

Fighting Depression: TMS and ECT are Sought-After Treatments

Elizabeth See struggled with depression for more than a decade when, in November 2014, she was diagnosed with Goodpasture syndrome, a rare autoimmune disease that attacks the kidneys and lungs. A tennis professional, she suddenly found her livelihood and passion restricted by physical constraints and regular dialysis treatments. TMS and ECT are increasingly sought-after treatments for depression...

How to Build a Strong Partners-ship

As an avid runner and diehard Red Sox fan, Brent P. Forester, MD, MSc, is no stranger to challenges. It was no surprise when he was asked, in 2015, to take on two taxing but critical roles—chief of the Division of Geriatric Psychiatry at McLean Hospital and medical director for Behavioral Health within Population Health Management at Partners HealthCare—that he eagerly said yes....

Depression Screening for All Adults Deserves a Thumbs Up

This week, the US Preventive Services Task Force recommended that primary care physicians screen all adult patients, including pregnant women and new moms, for depression, and that’s good news for improving quality of care and quality of life for individuals and their families while also helping to contain health care costs. What is Depression? Everyone occasionally feels blue or sad, but...

Donors Fuel Research Into Depression, World’s Leading Cause of Disability

For much of the last century, depression has been viewed largely as a single disease; however, it is an extraordinarily heterogeneous condition. Consequently, predicting which healthy people will develop depression is challenging. Given that approximately half of patients do not respond to current options for care, finding the right treatment is equally difficult. Clearly, further study is needed...

Q & A: Kerry J. Ressler, MD, PhD, Chief Scientific Officer and Chief of the Center of Excellence in Depression and Anxiety Disorders

Kerry J. Ressler, MD, PhD, arrived at McLean in August as Chief Scientific Officer and the inaugural chief of McLean’s new Center of Excellence in Depression and Anxiety Disorders. He also holds the James and Patricia Poitras Endowed Chair in Psychiatry, thanks to a generous gift from longtime donors Patricia and James Poitras. Dr. Ressler’s research examines how fear works in the...

McLean Hospital Brain Imaging Study Offers New Insight into Depression

According to the World Health Organization, globally, an estimated 350 million people of all ages suffer from depression. Now, thanks to a new brain imaging study conducted at McLean Hospital, the largest psychiatric affiliate of Harvard Medical School, we have new insights into the brain circuitry of someone with a history of depression. In their paper, “Corticostriatal Pathways...

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