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Diego Pizzagalli Related Content


McLean Scientists: Brain Activity Can Predict Success of Depression Treatment

McLean Hospital and Harvard Medical School researchers believe they have uncovered a method that could be useful in predicting a depressed patient’s treatment prognosis, prior to starting treatment. In the paper “Pretreatment Rostral Anterior Cingulate Cortex Activity in Relation to Symptom Improvement in Depression: A Randomized Clinical Trial,” available online and in the June 2018 edition of...

Pizzagalli Receives 2017 Joel Elkes Research Award

On December 4, 2017, the American College of Neuropsychopharmacology (ACNP) honored McLean Hospital’s Diego A. Pizzagalli, PhD, with the 2017 Joel Elkes Research Award. The ACNP presents this annual award in recognition of a scientist’s outstanding clinical contribution to neuropsychopharmacology. The contribution may be based on a single discovery or a cumulative body of work. Pizzagalli, who...

Understanding the Biology Behind Major Depressive Disorder

Major depressive disorder (MDD) affects about 7% of people in the United States each year. Although researchers and clinicians know that stressful life events can trigger a depressive episode, the biological mechanisms behind it are not well understood. Studies led by Diego A. Pizzagalli, PhD, director of the Center for Depression, Anxiety and Stress Research (CDASR) at McLean Hospital, aim to...

Faster. Better. More Precise: McLean’s New Siemens Prisma 3T MRI Scanner Provides Incredible Insights

Since its invention more than 40 years ago, magnetic resonance imaging (MRI) technology has allowed clinicians and researchers to produce more precise images of the human body and gain a greater understanding of injuries and disease. For McLean’s Scott E. Lukas, PhD, and Diego A. Pizzagalli, PhD, recent improvements in MRI technology hold tremendous potential for the study of brain function,...

Manton Foundation Funds State of the Art MRI Scanner

Scott E. Lukas, PhD, director of the McLean Imaging Center (MIC), can barely contain his excitement when describing McLean’s new 3 Tesla Siemens PRISMA MRI scanner. An extraordinary $3.75M grant from the Manton Foundation funded this state of the art acquisition. According to Lukas and fellow MIC Director Diego A. Pizzagalli, PhD, the new machine will enable McLean to take a huge leap forward in...

New MRI Scanner Will Increase Researchers’ Impact and Help Hospital Compete for Grants

The arrival of a new magnetic resonance imaging (MRI) scanner for the McLean Imaging Center (MIC) last week will help investigators significantly expand their research scope, provide a more comfortable experience for patients, and position the hospital to better compete for grants and other funding. The acquisition of the Siemens Prisma 3T MRI scanner was made possible by a $3.75 million grant...

Donors Fuel Research Into Depression, World’s Leading Cause of Disability

For much of the last century, depression has been viewed largely as a single disease; however, it is an extraordinarily heterogeneous condition. Consequently, predicting which healthy people will develop depression is challenging. Given that approximately half of patients do not respond to current options for care, finding the right treatment is equally difficult. Clearly, further study is needed...

McLean Hospital Brain Imaging Study Offers New Insight into Depression

According to the World Health Organization, globally, an estimated 350 million people of all ages suffer from depression. Now, thanks to a new brain imaging study conducted at McLean Hospital, the largest psychiatric affiliate of Harvard Medical School, we have new insights into the brain circuitry of someone with a history of depression. In their paper, “Corticostriatal Pathways Contribute to...

The O’Keefe Awards: Catalyzing Research, Jump-Starting Careers

One researcher is looking at how administering xenon gas may minimize injury to a traumatized brain. Another is studying how childhood sexual abuse affects brain function and increases the risk of re-victimization. A third is trying to understand the connection between early tobacco use and later vulnerability to drug abuse. Each study is likely to make important contributions to the field of...

Turning Promise into Practice: Nurturing Young Researchers Through Donor-Supported Fellowships

The future of brain science lies in researchers like Poornima Kumar, a 30-year-old neuroscientist with the mind of a mathematician, the expertise of an engineer, and a PhD in neuroimaging. Kumar, the hospital’s first John and Charlene Madison Cassidy Fellow in Translational Neuroscience, works in that sweet spot where neuroanatomy meets mathematics. She uses computational models—the concepts and...

McLean Launches Center for Depression, Anxiety and Stress Research

Depression, anxiety, and stress are a debilitating triad. About one in six Americans will suffer from depression at some point in his or her life; one in four will struggle with an anxiety disorder. Often, the two go hand in hand, triggered by stressors like childhood neglect or the death of a loved one. Left untreated or not accurately diagnosed, these disorders can negatively impact every facet...

McLean Hospital Center for Depression, Anxiety and Stress Research to Host Inaugural Event October 1

McLean Hospital’s newly established Center for Depression, Anxiety and Stress Research will host an inaugural event on Friday, Oct. 1 from 1:15pm to 3:30pm in Pierce Hall, located on McLean’s Belmont campus. The event, which is free and open to the public, will feature brief presentations by more than 20 members of the McLean and Harvard faculty on clinical and research programs relevant to...