In the Media: How To Fight Depression? Faster
Dr. Diego A. Pizzagalli describes the goal of his research assessing depression severity and treatment options.
Diego Pizzagalli Related Content
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In the Media: Found – A Brain-Wiring Pattern Linked to Depression
Dr. Diego A. Pizzagalli offers an independent review of a recent study that found a specific brain network to be larger in individuals with depression.
Neurotherapeutics Offer Hope for Treatment-Resistant Depression
As a young psychiatrist, Stephen J. Seiner, MD, witnessed how effective electroconvulsive therapy (ECT) was for some of the depressed patients he encountered during a geriatric fellowship at McLean. “I saw how lifesaving it could be for patients who did not respond to medication,” said Seiner. After...
Wellcome Leap Trial Aims To Improve Depression Care Through Precision Medicine
Depression has become the leading cause of disability worldwide across all illnesses, according to the World Health Organization. In only a single year, 264 million people deal with depression, and 800,000 lives are lost to suicide. Yet psychiatrists are often forced to resort to a trial-and-error...
In the Media: The Magic Pill Club
Drs. James I. Hudson and Diego A. Pizzagalli describe how the body reacts and processes mental health medications.
In the Media: Predictive Biomarkers Could Ease the Exhaustive Trial-and-Error of Antidepressants
Dr. Diego A. Pizzagalli’s clinical trial using MRIs to assess antidepressant effectiveness is featured.
McLean Hospital and GrayMatters Health Awarded a BIRD Foundation Grant
GrayMatters Health, a digital therapeutics start-up company, announced that the BIRD Israel-U.S. Binational Industrial Research and Development Foundation awarded a grant to McLean Hospital and the company to develop a novel solution for the therapy of major depressive disorder (MDD) with anhedonia...
Conte Center Grant Expands Studies of Brain Mechanisms Behind Depression and Anxiety
With a $15,973,571, five-year grant from the National Institute of Mental Health (NIMH), investigators from McLean Hospital and four other institutions will further their studies into the brain mechanisms behind depression and anxiety. Under the title “Novel Treatment Targets for Affective Disorders...
Diego Pizzagalli, PhD, Named Editor of Cognitive, Affective & Behavioral Neuroscience
McLean Hospital’s Diego A. Pizzagalli, PhD, has been named editor of the journal Cognitive, Affective, & Behavioral Neuroscience (CABN). Pizzagalli’s tenure as editor begins on January 1, 2021. Published six times each year, the publication presents empirical articles and reviews on behavior and...
Philanthropy Bolsters Research Into Teen Depression
How do you predict which teenagers will develop clinical depression? Can you use brain activity, mood or behavior patterns, and other information? Are there targeted prevention strategies that could stop a vulnerable young person from plunging into depression? And for teenagers who are currently...
McLean Scientists: Brain Activity Can Predict Success of Depression Treatment
McLean Hospital and Harvard Medical School researchers believe they have uncovered a method that could be useful in predicting a depressed patient’s treatment prognosis, prior to starting treatment. In the paper “ Pretreatment Rostral Anterior Cingulate Cortex Activity in Relation to Symptom...
Pizzagalli Receives 2017 Joel Elkes Research Award
On December 4, 2017, the American College of Neuropsychopharmacology (ACNP) honored McLean Hospital’s Diego A. Pizzagalli, PhD, with the 2017 Joel Elkes Research Award. The ACNP presents this annual award in recognition of a scientist’s outstanding clinical contribution to neuropsychopharmacology...
Understanding the Biology Behind Major Depressive Disorder
Major depressive disorder (MDD) affects about 7% of people in the United States each year. Although researchers and clinicians know that stressful life events can trigger a depressive episode, the biological mechanisms behind it are not well understood. Studies led by Diego A. Pizzagalli, PhD...
Faster. Better. More Precise: McLean’s New Siemens Prisma 3T MRI Scanner Provides Incredible Insights
Since its invention more than 40 years ago, magnetic resonance imaging (MRI) technology has allowed clinicians and researchers to produce more precise images of the human body and gain a greater understanding of injuries and disease. For McLean’s Scott E. Lukas, PhD, and Diego A. Pizzagalli, PhD...
Manton Foundation Funds State of the Art MRI Scanner
Scott E. Lukas, PhD, director of the McLean Imaging Center (MIC), can barely contain his excitement when describing McLean’s new 3 Tesla Siemens PRISMA MRI scanner. An extraordinary $3.75M grant from the Manton Foundation funded this state of the art acquisition. According to Lukas and fellow MIC...
Donors Fuel Research Into Depression, World’s Leading Cause of Disability
For much of the last century, depression has been viewed largely as a single disease; however, it is an extraordinarily heterogeneous condition. Consequently, predicting which healthy people will develop depression is challenging. Given that approximately half of patients do not respond to current...
The O’Keefe Awards: Catalyzing Research, Jump-Starting Careers
One researcher is looking at how administering xenon gas may minimize injury to a traumatized brain. Another is studying how childhood sexual abuse affects brain function and increases the risk of re-victimization. A third is trying to understand the connection between early tobacco use and later...
Turning Promise Into Practice: Nurturing Young Researchers Through Donor-Supported Fellowships
The future of brain science lies in researchers like Poornima Kumar, a 30-year-old neuroscientist with the mind of a mathematician, the expertise of an engineer, and a PhD in neuroimaging. Kumar, the hospital’s first John and Charlene Madison Cassidy Fellow in Translational Neuroscience, works in...
McLean Launches Center for Depression, Anxiety and Stress Research
Depression, anxiety, and stress are a debilitating triad. About one in six Americans will suffer from depression at some point in his or her life; one in four will struggle with an anxiety disorder. Often, the two go hand in hand, triggered by stressors like childhood neglect or the death of a loved...
