Translational Research Related Content
Baszucki Group announced the launch of a new partnership with McLean Hospital for a clinical trial of a therapeutic ketogenic diet for bipolar disorder. A cross-disciplinary team at the McLean OnTrack™ program will investigate nutritional ketosis as both a novel treatment strategy and a critical...
Depression has become the leading cause of disability worldwide across all illnesses, according to the World Health Organization. In only a single year, 264 million people deal with depression , and 800,000 lives are lost to suicide . Yet psychiatrists are often forced to resort to a trial-and-error...
Dr. Amber N. Edinoff and colleagues review the scientific literature of the antidepressant tianeptine and find a need for more regulation.
Dr. Ann K. Shinn comments on the findings of a clinical trial examining a new antipsychotic medication.
Dr. Joshua C. Brown finds that long-term caffeine users may exhibit decreased brain plasticity.
In the Media: Can Magnesium and Vitamin D3 Curb Anxiety? Mental Health Experts Weigh In on a Viral TikTok Claim
Dr. Christopher M. Palmer shares research examining the effectiveness of magnesium supplements to treat the symptoms of anxiety disorders.
The research of Dr. Staci Gruber is referenced in this opinion piece.
Dr. Staci Gruber discusses the landscape of CBD research and advises CBD users to work in collaboration with their medical team.
Irritability is the most common reason children are brought for psychiatric evaluation. It is a diagnostic criterion or associated symptom for multiple diagnoses listed in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Over the past 20 years, much has been learned...
Single-Cell Study Reveals Genes That May Be Involved in Post-Traumatic Stress and Major Depressive Disorders
An international team led by investigators at McLean Hospital analyzed the genes expressed in approximately 575,000 individual cells from the brains of people with and without post-traumatic stress and major depressive disorders (PTSD and MDD), revealing new insights into the mechanisms behind the...
Much research on treatment of substance use disorders (SUDs) focuses on reducing symptoms like depression and cravings. However, a growing body of literature examines the role of grit, gratitude, happiness, and other positive psychological constructs, including optimism. Dispositional optimism—the...
Cell therapy holds promise as a new treatment for Parkinson’s disease, but in many trials to date, most transplanted dopamine cells have failed to survive, raising a fundamental obstacle. Recent advancements led by researchers at McLean Hospital and Massachusetts General Hospital could change this...
The research of Dr. Milissa Kaufman is noted in an article about dissociation.
Dr. Martin Teicher discusses his work studying the long-term effects of childhood maltreatment.
Dr. Marisa M. Silveri outlines the research findings that reveal what may be contributing to the mental health issues of adolescent girls.
Honoring Andrea M. Cataldo, PhD , and Antonia V. Seligowski, PhD, McLean Hospital – The Alfred Pope Award for Early Career Investigators Each year, McLean Hospital recognizes young researchers with the Alfred Pope Award for Early Career Investigators. The honor is named for one of the hospital’s...
Dr. Staci Gruber discusses the research examining how medical cannabis can affect sleep health.
Dr. Brent P. Forester offers feedback regarding the results of a new Alzheimer’s disease drug trial.
In the Media: Cognition After NFL Retirement Worse in Players With Concussion Symptoms During Career
Dr. Laura Germine and colleagues find that football players who reported concussion symptoms after they retired performed worse on cognitive tests than nonplayers.
Drs. James I. Hudson and Diego A. Pizzagalli describe how the body reacts and processes mental health medications.