Mclean Hospital

Parkinson’s Disease Related Content


Researchers Find That Lipid Accumulation in the Brain May Be an Early Sign of Parkinson’s Disease

A collaborative team of researchers at McLean Hospital, a Harvard Medical School affiliate, and the University of Oxford has found that elevated levels of certain types of lipids (fat molecules) in the brain may be an early sign of Parkinson’s disease (PD). This finding could have significant implications for identifying patients who may be at risk for developing PD and for the early treatment of...

Personalizing Stem Cell Therapy for Parkinson’s Disease

In the United States alone, as many as one million people have Parkinson’s disease (PD), with approximately 60,000 cases being diagnosed each year, according to the Parkinson’s Disease Foundation. Kwang-Soo Kim, PhD, director of the Molecular Neurobiology Laboratory at McLean Hospital and professor of psychiatry at Harvard Medical School, is committed to finding a way to lower those numbers. Kim...

Fighting Parkinson’s in the Lab

I had the privilege of meeting Muhammad Ali a number of times, and while the Parkinson’s disease that ravaged his brain had already reduced his ability to communicate verbally—it never diminished his spirit or his will to keep fighting. Like Michael J. Fox, with whom I’ve spoken before Congress about Parkinson’s research funding, Mr. Ali had a strength and a drive to raise awareness about...

Team Led by McLean Hospital Researcher Uncovers Potential Parkinson’s Treatment

Kwang-Soo Kim, PhD, director of McLean Hospital’s Molecular Neurobiology Laboratory and professor of psychiatry at Harvard Medical School, along with collaborative teams from Brandeis University and Nanyang Technological University (NTU) in Singapore, recently announced the findings of a multi-year research project that shows that existing anti-malaria drugs may have the ability to treat...

McLean Hospital Researchers See Promise in Transplanted Fetal Stem Cells for Parkinson’s

Researchers at Harvard-affiliated McLean Hospital have found that fetal dopamine cells transplanted into the brains of patients with Parkinson’s disease were able to remain healthy and functional for up to 14 years, a finding that could lead to new and better therapies for the illness. The discovery, reported in the June 5, 2014 issue of the journal Cell Reports, could pave the way for...

Pope Francis Invites Stem Cell Researcher Ole Isacson to Present at the Vatican

Ole Isacson, Dr Med Sci, director of the Neuroregeneration Research Institute at McLean Hospital and one of the world’s preeminent experts in the use of stem cell therapies to treat neurodegenerative diseases such as Parkinson’s disease and Huntington’s disease, was recently invited by Pope Francis to present his work at the Vatican. More than 700 people, including doctors, health care...

Oeystein R. Brekk, PhD

Oeystein R. Brekk, PhD, is currently working as a post-doctoral research fellow at McLean Hospital in the lab of Dr. Hallett. His research interests include cellular lipid and protein degradation systems—and their malfunction—in relation to Parkinson’s disease and other synucleinopathies. Prior to working at McLean Hospital, Dr. Brekk was a Marie Curie fellow working at the Academy of Athens,...

Penny Hallett, PhD

Penny Hallett, PhD, is an assistant professor of psychiatry at Harvard Medical School and co-director of the Neuroregeneration Research Institute (NRI). She received her PhD from the University of Manchester, UK, and completed post-doctoral studies at Massachusetts General Hospital, moving in 2006 to McLean Hospital to join the NRI. Dr. Hallett served as an editor for Molecular and Cellular...

Ole Isacson, Dr Med Sci

Dr. Ole Isacson is a professor of neurology at Harvard Medical School and founding director of the Neuroregeneration Research Institute at McLean Hospital. His work is focused on the understanding and treatments of neurodegenerative disease, with particular emphasis on distinguishing critical mechanisms and treatments of neuronal vulnerability at the onset of disease, or new restorative...

Kwang-Soo Kim, PhD

Kwang-Soo Kim, PhD, has over 25 years of experience investigating molecular and developmental neurobiology of the midbrain dopamine neuronal system in health and disease, focusing on elucidating the transcriptional mechanisms underlying development and maintenance of dopamine neurons. Based on basic transcriptional studies of midbrain dopamine neurons, Dr. Kim’s lab identified the orphan nuclear...

Woori Kim, PhD

Woori Kim, PhD, received her BSc, MSc, and PhD in biochemistry from Hanyang University. She joined the Molecular Neurobiology Laboratory in 2014 as a post-doctoral fellow.

Sanghyeok Ko, PhD

Sanghyeok Ko PhD, focuses on developing a human induced pluripotent stem (hiPS) cell generation method using non-viral delivery of reprogramming genes. To overcome the limitation of possible tumorigenesis in hiPS cells, several chromosome nonintegrating reprogramming methods have been developed using recombinant reprogramming proteins or episomal plasmids. With these methods many human iPS cell...

Joanna A. Korecka, PhD

Joanna A. Korecka, PhD is a post-doctoral research fellow at the Neuroregeneration Research Institute at McLean Hospital. Her research focuses on elucidating biological processes involved with neuronal degeneration in Parkinson’s disease (PD). During her PhD studies, she engaged in identifying new molecular candidates responsible for the development of PD. Currently, she continues to investigate...

Pierre R. Leblanc, PhD

Pierre R. Leblanc, PhD, received his BSc in Biochemistry from McGill University and his PhD in Biochemistry from McMaster University, studying membranes biogenesis. He performed his post-doctoral work at the Massachusetts Institute of Technology, focusing on the gamma/delta T-cell receptor rearrangements and at Tufts University Medical School, investigating pathogenic Vbeta T-cell receptor usage...

Teresia Osborn, PhD

Teresia Osborn, PhD, graduated from Gothenburg University with a MS in pharmaceutical bioscience in 2002 and a PhD in leukocyte biology in 2007. Throughout her graduate studies she was also a research fellow at the Division of Translational Medicine at Brigham and Women’s Hospital. She joined the Neuroregeneration Research Institute at McLean Hospital as a post-doctoral research fellow in 2008....

Bin Song, PhD

Bin Song, PhD, works on signaling transduction and gene regulation of neuronal survival and apoptosis (programmed cell death) in service of the development of new therapeutic targets for treatment of neurodegenerative diseases such as Parkinson’s disease (PD). Dr. Song’s early research was focused on the role of certain proteins during neuron survival/apoptosis. Understanding the cellular...

Kai-Christian Sonntag, MD, PhD

As a graduate of University of Heidelberg Medical School, Dr. Sonntag studied the molecular biology of viruses, and as a research fellow at the Transplantation Biology Research Center at Massachusetts General Hospital, he conducted research in transplantation immunology. In 2000, he joined McLean Hospital where his laboratory is integrated in the Program for Neuropsychiatric Research, directed by...

Anna W. Sromek, PhD

Anna W. Sromek, PhD, received her BS in chemistry at the University of Chicago in 1996, and PhD in organic chemistry at the University of Illinois at Chicago in 2005. She was a NIDA post-doctoral research fellow at McLean Hospital from 2008 to 2010, and a recipient of the Alfred Pope Award for Young Investigators in 2011. Dr. Sromek is currently the associate director of the Medicinal Chemistry...

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