Mclean Hospital
Brian Brennan, MD

Brian P. Brennan, MD, MMSc

McLean Hospital Title:
Harvard Medical School Title:
  • Assistant Professor of Psychiatry


Brian P. Brennan, MD, MMSc, is an assistant professor of psychiatry at Harvard Medical School and is the medical director of the Obsessive Compulsive Disorder Institute at McLean Hospital—a world-renowned intensive residential treatment facility for patients with severe OCD and related disorders. He is also the associate director of translational neuroscience research in the Biological Psychiatry Laboratory at McLean Hospital and has published extensively on the use of neuroimaging to investigate neurochemical and neurobiological abnormalities underlying psychiatric disorders such as OCD and depression.

The primary focus of Dr. Brennan’s research is the identification of novel biological targets for the development of improved therapeutics for OCD and related disorders. He has received grant funding from the National Institute of Mental Health, NARSAD, the Sidney R. Baer Jr. Foundation, and the Stanley Medical Research Institute.


OCDDepressionAnxietyTranslational Research


PubMed search for Dr. Brennan

Education & Training:

  • 1994 BA, University of Pennsylvania
  • 2000 MD, University of Pennsylvania School of Medicine
  • 2009 MMSc, Harvard-MIT Division of Health Sciences and Technology
  • 2000-2001 Preliminary Internship in Internal Medicine, Pennsylvania Hospital
  • 2001-2004 Residency in Psychiatry, Massachusetts General Hospital/McLean Hospital
  • 2003-2004 Administrative Chief Resident, McLean Hospital
  • 2005-2007 Clinical Trials Fellowship, Biological Psychiatry Laboratory, McLean Hospital
  • 2007-2009 Clinical Investigator Training Program, Harvard-MIT Division of Health Sciences and Technology/Beth Israel Deaconess Medical Center, in collaboration with Pfizer and Merck
Board Certifications:
  • 2001 Massachusetts Medical License Registration
  • 2005 Psychiatry, American Board of Psychiatry and Neurology




Office Address:

Belmont campus - Oaks Building